Ethyl 3,6-dichloropyridazine-4-carboxylate

Base Information

Chemical Name:Ethyl 3,6-dichloropyridazine-4-carboxylate
CAS No.:34127-22-5
Molecular Formula:C7H6 Cl2 N2 O2
Molecular Weight:221.043
Hs Code.:2933990090
European Community (EC) Number:857-713-2
DSSTox Substance ID:DTXSID70576449
Wikidata:Q82466158
Mol file:34127-22-5.mol

Synonyms:ETHYL 3,6-DICHLOROPYRIDAZINE-4-CARBOXYLATE;34127-22-5;C7H6Cl2N2O2;MFCD08704423;4-Pyridazinecarboxylic acid, 3,6-dichloro-, ethyl ester;SCHEMBL140932;DTXSID70576449;KVWIASCXKZVAQG-UHFFFAOYSA-N;AMY31041;BCP19398;AKOS015995092;AB48559;CS-W020493;AS-48750;SY108514;2-CHLOROETHYLPHOSPHORICACIDDICHLORIDE;EN300-370955;F53192;Z1269223827

Suppliers and Price of Ethyl 3,6-dichloropyridazine-4-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Ethyl3,6-Dichloropyridazine-4-carboxylate
10mg
$ 45.00

Matrix Scientific
Ethyl 3,6-dichloropyridazine-4-carboxylate 97%
1g
$ 874.00

Crysdot
Ethyl3,6-dichloropyridazine-4-carboxylate 95+%
25g
$ 594.00

Crysdot
Ethyl3,6-dichloropyridazine-4-carboxylate 95+%
10g
$ 347.00

ChemScene
Ethyl3,6-dichloropyridazine-4-carboxylate
10g
$ 330.00

ChemScene
Ethyl3,6-dichloropyridazine-4-carboxylate
1g
$ 67.00

ChemScene
Ethyl3,6-dichloropyridazine-4-carboxylate
5g
$ 189.00

Chemenu
Ethyl3,6-dichloropyridazine-4-carboxylate 95%
5g
$ 242.00

Chemenu
Ethyl3,6-dichloropyridazine-4-carboxylate 95%
10g
$ 339.00

Chemenu
Ethyl3,6-dichloropyridazine-4-carboxylate 95%
25g
$ 585.00

Total 29 raw suppliers

Chemical Property of Ethyl 3,6-dichloropyridazine-4-carboxylate

Chemical Property:

Boiling Point:364.2±37.0 °C(Predicted)
PKA:-3.52±0.10(Predicted)
PSA：52.08000
Density:1.433±0.06 g/cm3(Predicted)
LogP:1.96010
Storage Temp.:Inert atmosphere,Store in freezer, under -20°C
XLogP3:2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:219.9806328
Heavy Atom Count:13
Complexity:191

Purity/Quality:

99%, ^*data from raw suppliers

Ethyl3,6-Dichloropyridazine-4-carboxylate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=CC(=NN=C1Cl)Cl

Technology Process of Ethyl 3,6-dichloropyridazine-4-carboxylate

There total 6 articles about Ethyl 3,6-dichloropyridazine-4-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 96042-30-7
4-(dicyanomethylene)-2-methyl-6-(p-dimethylaminostyryl)-4H-pyran

: 51149-08-7
3,6-dichloropyridazin-4-carboxylic acid

: 34127-22-5
ethyl 3,6-dichloropyridazine-4-carboxylate

Guidance literature:: With thionyl chloride; In ethanol;

Reference yield: 77.0%

: 64-17-5
ethanol

: 51149-08-7
3,6-dichloropyridazin-4-carboxylic acid

: 34127-22-5
ethyl 3,6-dichloropyridazine-4-carboxylate

Guidance literature:: With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In tetrahydrofuran; at 20 ℃; for 16h;

Reference yield:

: 19064-64-3
3,6-dichloro-4-methylpyridazine

: 34127-22-5
ethyl 3,6-dichloropyridazine-4-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: 8.1 g / K₂Cr₂O₇, conc. H₂SO₄ / 2 h / 35 - 40 °C

2: 61 percent / (dimethylamino)pyridine, 1-<3-(dimethylamino)propyl>-3-ethylcarbodiimide hydrochloride / tetrahydrofuran / Ambient temperature

With dmap; potassium dichromate; sulfuric acid; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In tetrahydrofuran;
DOI:10.1021/jm00070a012