6-(tert-butyldimethylsilyloxy)-6-(4-(tert-butyldimethylsilyloxy)phenyl)-1-(2,2-dimethyl-4-oxo-4H-1,3-dioxin-6-yl)hexane-2,4-dione

Base Information

Chemical Name:6-(tert-butyldimethylsilyloxy)-6-(4-(tert-butyldimethylsilyloxy)phenyl)-1-(2,2-dimethyl-4-oxo-4H-1,3-dioxin-6-yl)hexane-2,4-dione
CAS No.:1449521-90-7
Molecular Formula:C₃₀H₄₈O₇Si₂
Molecular Weight:576.878
Hs Code.:

Synonyms:6-(tert-butyldimethylsilyloxy)-6-(4-(tert-butyldimethylsilyloxy)phenyl)-1-(2,2-dimethyl-4-oxo-4H-1,3-dioxin-6-yl)hexane-2,4-dione

Suppliers and Price of 6-(tert-butyldimethylsilyloxy)-6-(4-(tert-butyldimethylsilyloxy)phenyl)-1-(2,2-dimethyl-4-oxo-4H-1,3-dioxin-6-yl)hexane-2,4-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 6-(tert-butyldimethylsilyloxy)-6-(4-(tert-butyldimethylsilyloxy)phenyl)-1-(2,2-dimethyl-4-oxo-4H-1,3-dioxin-6-yl)hexane-2,4-dione

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 6-(tert-butyldimethylsilyloxy)-6-(4-(tert-butyldimethylsilyloxy)phenyl)-1-(2,2-dimethyl-4-oxo-4H-1,3-dioxin-6-yl)hexane-2,4-dione

There total 5 articles about 6-(tert-butyldimethylsilyloxy)-6-(4-(tert-butyldimethylsilyloxy)phenyl)-1-(2,2-dimethyl-4-oxo-4H-1,3-dioxin-6-yl)hexane-2,4-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 1449521-91-8
3-(tert-butyldimethylsilyloxy)-3-(4-(tert-butyldimethylsilyloxy) phenyl)-N-methoxy-N-methylpropanamide

: 130473-38-0
2,2-dimethyl-6-(2-oxo-2-methylethyl)-4H-1,3-dioxin-4-one

: 1449521-90-7
6-(tert-butyldimethylsilyloxy)-6-(4-(tert-butyldimethylsilyloxy)phenyl)-1-(2,2-dimethyl-4-oxo-4H-1,3-dioxin-6-yl)hexane-2,4-dione

Guidance literature:: 2,2-dimethyl-6-(2-oxo-2-methylethyl)-4H-1,3-dioxin-4-one; With lithium diisopropyl amide; In tetrahydrofuran; at -78 ℃; for 1h;

With diethylzinc; In tetrahydrofuran; hexane; at -78 ℃; for 0.333333h;

3-(tert-butyldimethylsilyloxy)-3-(4-(tert-butyldimethylsilyloxy) phenyl)-N-methoxy-N-methylpropanamide; In tetrahydrofuran; hexane; at -25 - -5 ℃; for 2h;
DOI:10.1016/j.tetlet.2013.05.044

Reference yield:

: C₂₃H₄₂O₄Si₂

: 1449521-90-7
6-(tert-butyldimethylsilyloxy)-6-(4-(tert-butyldimethylsilyloxy)phenyl)-1-(2,2-dimethyl-4-oxo-4H-1,3-dioxin-6-yl)hexane-2,4-dione

Guidance literature:: Multi-step reaction with 2 steps

1.1: isopropylmagnesium chloride / tetrahydrofuran / 0.42 h / -40 °C

2.1: lithium diisopropyl amide / tetrahydrofuran / 1 h / -78 °C

2.2: 0.33 h / -78 °C

2.3: 2 h / -25 - -5 °C

With isopropylmagnesium chloride; lithium diisopropyl amide; In tetrahydrofuran;
DOI:10.1016/j.tetlet.2013.05.044

Reference yield:

: 2881-83-6
ethyl 4-methoxybenzoylacetate

: 1449521-90-7
6-(tert-butyldimethylsilyloxy)-6-(4-(tert-butyldimethylsilyloxy)phenyl)-1-(2,2-dimethyl-4-oxo-4H-1,3-dioxin-6-yl)hexane-2,4-dione

Guidance literature:: Multi-step reaction with 5 steps

1.1: boron tribromide / dichloromethane / 3.5 h / -78 - -15 °C

2.1: sodium tetrahydroborate; ethanol / 3 h / 0 °C

3.1: 1H-imidazole / dichloromethane / 18 h / 23 °C

4.1: isopropylmagnesium chloride / tetrahydrofuran / 0.42 h / -40 °C

5.1: lithium diisopropyl amide / tetrahydrofuran / 1 h / -78 °C

5.2: 0.33 h / -78 °C

5.3: 2 h / -25 - -5 °C

With 1H-imidazole; sodium tetrahydroborate; ethanol; isopropylmagnesium chloride; boron tribromide; lithium diisopropyl amide; In tetrahydrofuran; dichloromethane;
DOI:10.1016/j.tetlet.2013.05.044