N-[2-(4-chlorophenyl)prop-2-en-1-yl]-N-(p-toluenesulfonyl)amide

Base Information

• Chemical Name: N-[2-(4-chlorophenyl)prop-2-en-1-yl]-N-(p-toluenesulfonyl)amide
• CAS No.: 1254470-60-4
• Molecular Formula: C₁₆H₁₆ClNO₂S
• Molecular Weight: 321.828
• Mol file: 1254470-60-4.mol

Synonyms:N-[2-(4-chlorophenyl)prop-2-en-1-yl]-N-(p-toluenesulfonyl)amide

Chemical Property of N-[2-(4-chlorophenyl)prop-2-en-1-yl]-N-(p-toluenesulfonyl)amide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-[2-(4-chlorophenyl)prop-2-en-1-yl]-N-(p-toluenesulfonyl)amide

There total 8 articles about N-[2-(4-chlorophenyl)prop-2-en-1-yl]-N-(p-toluenesulfonyl)amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

1-(4-chlorophenyl)-1-methyl-N-tosylaziridine → N-[2-(4-chlorophenyl)prop-2-en-1-yl]-N-(p-toluenesulfonyl)amide (1254470-60-4)

Guidance literature:

With (1,5-cyclooctadiene)(pyridine)(tricyclohexylphosphine)iridium(I) tetrakis[3,5-bis(trifluoromethyl)phenyl]borate; In dichloromethane; at 20 ℃; for 17h; Inert atmosphere; Sealed tube;

DOI:10.1021/acs.orglett.8b02450

Reference yield: 76.0%

chloroamine-T (127-65-1) + 3-(4-chlorophenyl)-3-butenoic acid (81187-88-4) → N-[2-(4-chlorophenyl)prop-2-en-1-yl]-N-(p-toluenesulfonyl)amide (1254470-60-4)

Guidance literature:

With iodine; In N,N-dimethyl-formamide; at 20 ℃; for 2h; regioselective reaction; Inert atmosphere;

DOI:10.1002/chem.201503298

Reference yield: 74.0%

4-toluenesulfonyl azide (941-55-9) + 1-chloro-4-(1-methylethenyl)-benzene (1712-70-5) → N-[2-(4-chlorophenyl)prop-2-en-1-yl]-N-(p-toluenesulfonyl)amide (1254470-60-4)

Guidance literature:

With (5,10,15,20-tetrakis(pentafluorophenyl)porphyrinato)iron(III) chloride; In 1,2-dichloro-ethane; for 24h; Molecular sieve; Inert atmosphere; Reflux;

DOI:10.1002/chem.201000581

upstream raw materials:

4-toluenesulfonyl azide

1-chloro-4-(1-methylethenyl)-benzene

chloroamine-T

3-(4-chlorophenyl)-3-butenoic acid