(S)-tert-butyl 3-hydroxypropyl(2-(2-nitrophenylsulfonylamide)propyl)carbamate

Base Information

Chemical Name:(S)-tert-butyl 3-hydroxypropyl(2-(2-nitrophenylsulfonylamide)propyl)carbamate
CAS No.:949109-35-7
Molecular Formula:C₁₇H₂₇N₃O₇S
Molecular Weight:417.483
Hs Code.:

Synonyms:(S)-tert-butyl 3-hydroxypropyl(2-(2-nitrophenylsulfonylamide)propyl)carbamate

Suppliers and Price of (S)-tert-butyl 3-hydroxypropyl(2-(2-nitrophenylsulfonylamide)propyl)carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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Total 1 raw suppliers

Chemical Property of (S)-tert-butyl 3-hydroxypropyl(2-(2-nitrophenylsulfonylamide)propyl)carbamate

Chemical Property:

Purity/Quality:: 95%-98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

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Useful:

Technology Process of (S)-tert-butyl 3-hydroxypropyl(2-(2-nitrophenylsulfonylamide)propyl)carbamate

There total 5 articles about (S)-tert-butyl 3-hydroxypropyl(2-(2-nitrophenylsulfonylamide)propyl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.7%

: 24424-99-5
di-tert-butyl dicarbonate

: 156-87-6
propan-1-ol-3-amine

: (S)-N-(1-methanesulfonyloxypropan-2-yl)-2-nitrobenzenesulfonamide

: 949109-35-7
(S)-tert-butyl 3-hydroxypropyl(2-(2-nitrophenylsulfonylamide)propyl)carbamate

Guidance literature:: propan-1-ol-3-amine; (S)-N-(1-methanesulfonyloxypropan-2-yl)-2-nitrobenzenesulfonamide; With potassium carbonate; In acetonitrile; at 70 ℃; for 2.5h; Large scale;

di-tert-butyl dicarbonate; In water; at 20 ℃; for 1.16667h; Large scale;

Reference yield:

: N-[(1S)-2-hydroxy-1-methylethyl]-2-nitrobenzenesulfonamide

: 949109-35-7
(S)-tert-butyl 3-hydroxypropyl(2-(2-nitrophenylsulfonylamide)propyl)carbamate

Guidance literature:: Multi-step reaction with 2 steps

1.1: 4-methyl-morpholine / dichloromethane / 20 h / -5 - 20 °C / Large scale

2.1: potassium carbonate / acetonitrile / 2.5 h / 70 °C / Large scale

2.2: 1.17 h / 20 °C / Large scale

With 4-methyl-morpholine; potassium carbonate; In dichloromethane; acetonitrile;

Reference yield:

: 1694-92-4
2-Nitrobenzenesulfonyl chloride

: 949109-35-7
(S)-tert-butyl 3-hydroxypropyl(2-(2-nitrophenylsulfonylamide)propyl)carbamate

Guidance literature:: Multi-step reaction with 3 steps

1.1: sodium hydrogencarbonate / water; tetrahydrofuran / 39 h / -8 - 20 °C / Large scale

2.1: 4-methyl-morpholine / dichloromethane / 20 h / -5 - 20 °C / Large scale

3.1: potassium carbonate / acetonitrile / 2.5 h / 70 °C / Large scale

3.2: 1.17 h / 20 °C / Large scale

With 4-methyl-morpholine; sodium hydrogencarbonate; potassium carbonate; In tetrahydrofuran; dichloromethane; water; acetonitrile;