2,3-Dimethyl-5-propylpyrazine

Base Information

Chemical Name:2,3-Dimethyl-5-propylpyrazine
CAS No.:32262-98-9
Molecular Formula:C₉H₁₄N₂
Molecular Weight:150.224
Hs Code.:2933990090
DSSTox Substance ID:DTXSID80334395
Nikkaji Number:J1.118.156B
Wikidata:Q82100176
Metabolomics Workbench ID:48758
Mol file:32262-98-9.mol

Synonyms:2,3-Dimethyl-5-propylpyrazine;32262-98-9;PYRAZINE, 2,3-DIMETHYL-5-PROPYL- (8CI,9CI);2,3-Dimethyl-5-n-propylpyrazine;Pyrazine, 2,3-dimethyl-5-propyl-;SCHEMBL9953811;DTXSID80334395;CHEBI:193684;AKOS006370456

Suppliers and Price of 2,3-Dimethyl-5-propylpyrazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 4 raw suppliers

Chemical Property of 2,3-Dimethyl-5-propylpyrazine

Chemical Property:

PSA：25.78000
LogP:2.04590
XLogP3:1.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:150.115698455
Heavy Atom Count:11
Complexity:114

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCC1=CN=C(C(=N1)C)C

Technology Process of 2,3-Dimethyl-5-propylpyrazine

There total 5 articles about 2,3-Dimethyl-5-propylpyrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

: 1147535-04-3
2,3-dimethyl-5-trifluoromethanesulfonyloxypyrazine

: 156567-57-6
propylzinc bromide

: 32262-98-9
2,3-Dimethyl-5-propylpyrazine

Guidance literature:: With 1,3-bis[(diphenylphosphino)propane]dichloronickel(II); In tetrahydrofuran; at 20 ℃; for 12h; Inert atmosphere;
DOI:10.1055/s-0031-1290972

Reference yield: 18.0%

: 1147535-04-3
2,3-dimethyl-5-trifluoromethanesulfonyloxypyrazine

: 77047-87-1
isopropyl zinc bromide

: 40790-21-4
5-isopropyl-2,3-dimethylpyrazine

: 32262-98-9
2,3-Dimethyl-5-propylpyrazine

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; at 20 ℃; for 12h; Inert atmosphere;
DOI:10.1055/s-0031-1290972

Reference yield:

: 57229-36-4
5,6-dimethyl-2-hydroxypyrazine

: 32262-98-9
2,3-Dimethyl-5-propylpyrazine

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine / chloroform / 2.5 h / -78 - 20 °C / Inert atmosphere

2: 1,3-bis[(diphenylphosphino)propane]dichloronickel(II) / tetrahydrofuran / 12 h / 20 °C / Inert atmosphere

With pyridine; 1,3-bis[(diphenylphosphino)propane]dichloronickel(II); In tetrahydrofuran; chloroform; 2: Negishi coupling reaction;
DOI:10.1055/s-0031-1290972