2-CHLOROETHANIMIDAMIDE HYDROCHLORIDE

Base Information

• Chemical Name: 2-CHLOROETHANIMIDAMIDE HYDROCHLORIDE
• CAS No.: 20846-52-0
• Molecular Formula: C2H5 Cl N2
• Molecular Weight: 92.5281
• Mol file: 20846-52-0.mol

Synonyms:2-Chloroacetamidine;Chloroacetamidine; Chloromethylcarboxamidine

Chemical Property of 2-CHLOROETHANIMIDAMIDE HYDROCHLORIDE

Chemical Property:

• Boiling Point: 146.4°Cat760mmHg
• PKA: 10.18±0.40(Predicted)
• Flash Point: 42.4°C
• PSA: 49.87000
• Density: 1.38g/cm³
• LogP: 0.96120

Purity/Quality:

97% ^*data from raw suppliers

2-Chloroacetamidine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-CHLOROETHANIMIDAMIDE HYDROCHLORIDE

There total 7 articles about 2-CHLOROETHANIMIDAMIDE HYDROCHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

chloroacetonitrile (107-14-2) → 2-chloro-acetamidine (20846-52-0)

Guidance literature:

chloroacetonitrile; With methanol; sodium; at 20 ℃; for 2h; Inert atmosphere;

With ammonium chloride; at 15 - 20 ℃; for 16.75h; Inert atmosphere;

Reference yield: 87.0%

acetamidine hydrochloride (124-42-5) → 2-chloro-acetamidine (20846-52-0)

Guidance literature:

With sodium hypochlorite; In water; at 0 ℃; for 2.5h;

Reference yield:

2-chloroethanimidic acid methyl ester (41264-52-2) → 2-chloro-acetamidine (20846-52-0)

Guidance literature:

With sodium methylate; ammonium chloride; In methanol; at 15 - 20 ℃; for 16h; Inert atmosphere;

upstream raw materials:

chloroacetonitrile

ethyl chloroacetimidate hydrochloride

acetamidine hydrochloride

2-chloroethanimidic acid methyl ester

Downstream raw materials:

4-Hydroxy-2-methyl-5-methoxypyrimidine

3-methyl-1,2,4-thiadiazol-5-amine

2-(chloromethyl)-5-(trifluoromethyl)pyrimidine

2-chloromethyl-3,5,7,8-tetrahydro-pyrano[4,3-d]pyrimidin-4-one