Saccharin N-(2-acetic acid ethyl ester)

Base Information

Chemical Name:Saccharin N-(2-acetic acid ethyl ester)
CAS No.:24683-20-3
Molecular Formula:C11H11 N O5 S
Molecular Weight:269.278
Hs Code.:2934999090
European Community (EC) Number:607-416-7
UNII:KN712V27AV
DSSTox Substance ID:DTXSID50179412
Wikidata:Q27282339
Pharos Ligand ID:TMQCL8GZ3Y2T
ChEMBL ID:CHEMBL3125563
Mol file:24683-20-3.mol

Synonyms:24683-20-3;Saccharin N-(2-acetic acid ethyl ester);Ethyl (1,1-dioxido-3-oxo-1,2-benzisothiazol-2(3H)-yl)acetate;ethyl 2-(1,1,3-trioxo-1,2-benzothiazol-2-yl)acetate;Saccharin N-(2-Acetic Acid Ethyl Ester)(Piroxicam Impurity E);Piroxicam impurity E [EP];UNII-KN712V27AV;KN712V27AV;CHEMBL3125563;ethyl (1,1-dioxido-3-oxo-1,2-benzothiazol-2(3H)-yl)acetate;Ethyl2,3-dihydro-3-oxo-1,2-benzisothiazole-2-acetate-1,1-dioxide;1,2-Benzisothiazole-2(3H)-acetic acid, 3-oxo-, ethyl ester, 1,1-dioxide;EC 607-416-7;ethyl 2-(1,1,3-trioxo-2,3-dihydro-1lambda6,2-benzothiazol-2-yl)acetate;Ethyl 2-(1,1-dioxido-3-oxobenzo[d]isothiazol-2(3H)-yl)acetate;(Piroxicam Impurity E)";ChemDiv1_000366;Oprea1_631494;Oprea1_858121;SCHEMBL14884779;HMS588A14;DTXSID50179412;HMS3429B03;BDBM50496460;MFCD00688886;STK136579;AKOS000418951;CCG-113731;(1,1,3-Trioxo-1,3-dihydro-1lambda*6*-benzo[d]isothiazol-2-yl)-acetic acid ethyl;PIROXICAM IMPURITY E [EP IMPURITY];CS-0127725;FT-0674495;EN300-299011;SR-01000398864;SR-01000398864-1;Q27282339;Z51115233;Ethyl 3-oxo-1,2-benzoisothiazoline-2-acetate 1,1-dioxide;Ethyl2-(1,1-dioxido-3-oxobenzo[d]isothiazol-2(3H)-yl)acetate;Benzo[d]isothiazol-3-one, 2-(2-ethoxy-2-oxoethyl)-, 1,1-dioxide;Ethyl (1,1-dioxido-3-oxo-1,2-benzisothiazol-2(3H)-yl)acetate #;ethyl 2-(1,1,3-trioxo-2,3-dihydro-1|E?,2-benzothiazol-2-yl)acetate

Suppliers and Price of Saccharin N-(2-acetic acid ethyl ester)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
SaccharinN-(2-AceticAcidEthylEster)(PiroxicamImpurityE)
250mg
$ 765.00

TRC
SaccharinN-(2-AceticAcidEthylEster)(PiroxicamImpurityE)
25mg
$ 115.00

Biosynth Carbosynth
3-Oxo-1,2-benzisothiazole-2(3H)-acetic acid ethyl ester 1,1-dioxide
250 mg
$ 150.00

Biosynth Carbosynth
3-Oxo-1,2-benzisothiazole-2(3H)-acetic acid ethyl ester 1,1-dioxide
100 mg
$ 100.00

Biosynth Carbosynth
3-Oxo-1,2-benzisothiazole-2(3H)-acetic acid ethyl ester 1,1-dioxide
50 mg
$ 57.50

American Custom Chemicals Corporation
PIROXICAM EP IMPURITY E 95.00%
5MG
$ 456.49

Total 13 raw suppliers

Chemical Property of Saccharin N-(2-acetic acid ethyl ester)

Chemical Property:

Vapor Pressure:5.45E-08mmHg at 25°C
Melting Point:106℃
Refractive Index:1.584
Boiling Point:441.4°C at 760 mmHg
PKA:-16.17±0.20(Predicted)
Flash Point:220.8°C
PSA：89.13000
Density:1.442g/cm³
LogP:1.41290
Storage Temp.:-20°C Freezer, Under inert atmosphere
Solubility.:Chloroform (Slightly), Ethyl Acetate (Slightly)
XLogP3:0.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:269.03579362
Heavy Atom Count:18
Complexity:453

Purity/Quality:

99.9% ^*data from raw suppliers

SaccharinN-(2-AceticAcidEthylEster)(PiroxicamImpurityE) ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)CN1C(=O)C2=CC=CC=C2S1(=O)=O
Uses Piroxicam impurity E.

Technology Process of Saccharin N-(2-acetic acid ethyl ester)

There total 11 articles about Saccharin N-(2-acetic acid ethyl ester) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%