phenyl N-(4-(6-carbamoyl-7-methoxy-4-quinolyl) oxy-2-fluorophenyl)carbamate

Base Information

Chemical Name:phenyl N-(4-(6-carbamoyl-7-methoxy-4-quinolyl) oxy-2-fluorophenyl)carbamate
CAS No.:417722-83-9
Molecular Formula:C₂₄H₁₈FN₃O₅
Molecular Weight:447.422
Hs Code.:

Synonyms:phenyl N-(4-(6-carbamoyl-7-methoxy-4-quinolyl) oxy-2-fluorophenyl)carbamate

Suppliers and Price of phenyl N-(4-(6-carbamoyl-7-methoxy-4-quinolyl) oxy-2-fluorophenyl)carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of phenyl N-(4-(6-carbamoyl-7-methoxy-4-quinolyl) oxy-2-fluorophenyl)carbamate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of phenyl N-(4-(6-carbamoyl-7-methoxy-4-quinolyl) oxy-2-fluorophenyl)carbamate

There total 4 articles about phenyl N-(4-(6-carbamoyl-7-methoxy-4-quinolyl) oxy-2-fluorophenyl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 417721-38-1
6-carbamoyl-4-(4-amino-3-fluorophenoxy)-7-methoxyquinoline

: 1885-14-9
phenyl chloroformate

: 417722-83-9
phenyl N-(4-(6-carbamoyl-7-methoxy-4-quinolyl) oxy-2-fluorophenyl)carbamate

Guidance literature:: With triethylamine; In dichloromethane; at 0 - 20 ℃; for 4h;

Reference yield:

: 417721-38-1
6-carbamoyl-4-(4-amino-3-fluorophenoxy)-7-methoxyquinoline

: 417722-83-9
phenyl N-(4-(6-carbamoyl-7-methoxy-4-quinolyl) oxy-2-fluorophenyl)carbamate

Guidance literature:

Reference yield:

: 417721-36-9
4‐chloro‐7‐methoxyquinoline‐6‐carboxamide

: 417722-83-9
phenyl N-(4-(6-carbamoyl-7-methoxy-4-quinolyl) oxy-2-fluorophenyl)carbamate

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydride / N,N-dimethyl-formamide / 0.5 h / 20 °C

1.2: 4 h / 60 °C

2.1: triethylamine / dichloromethane / 4 h / 0 - 20 °C

With sodium hydride; triethylamine; In dichloromethane; N,N-dimethyl-formamide;