Technology Process of 3-[(1E)-3,3-diethyltriaz-1-en-1-yl]-10-phenyl-10H-phenothiazine
There total 1 articles about 3-[(1E)-3,3-diethyltriaz-1-en-1-yl]-10-phenyl-10H-phenothiazine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
3-amino-10-phenyl-10H-phenothiazine;
With
boron trifluoride diethyl etherate;
In
dichloromethane;
at 0 ℃;
for 0.666667h;
Inert atmosphere;
With
tert.-butylnitrite;
In
dichloromethane;
at 0 ℃;
for 1h;
Inert atmosphere;
diethylamine;
With
potassium carbonate;
In
dichloromethane;
at 20 ℃;
for 20h;
Inert atmosphere;
DOI:10.1007/s11164-012-0642-6
- Guidance literature:
-
With
iodine; methyl iodide;
In
toluene;
at 55 ℃;
for 2h;
Inert atmosphere;
Sealed tube;
DOI:10.1007/s11164-012-0642-6
- Guidance literature:
-
Multi-step reaction with 4 steps
1: methyl iodide; iodine / toluene / 2 h / 55 °C / Inert atmosphere; Sealed tube
2: [1,1'-bis(diphenylphosphino)ferrocene]dichloropalladium(II); potassium acetate / dimethyl sulfoxide / 1 h / 80 °C / Inert atmosphere
3: palladium diacetate; caesium carbonate / N,N-dimethyl-formamide / 1 h / 110 °C / Inert atmosphere
4: bis-triphenylphosphine-palladium(II) chloride; N-ethyl-N,N-diisopropylamine; copper(l) iodide / tetrahydrofuran / 6 h / 70 °C / Inert atmosphere; Sealed tube
With
bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; [1,1'-bis(diphenylphosphino)ferrocene]dichloropalladium(II); iodine; potassium acetate; palladium diacetate; caesium carbonate; N-ethyl-N,N-diisopropylamine; methyl iodide;
In
tetrahydrofuran; dimethyl sulfoxide; N,N-dimethyl-formamide; toluene;
DOI:10.1007/s11164-012-0642-6
