8-phenoxycarbonyl-1,8-diazabicyclo[5.4.0]undec-7-enium chloride

Base Information

• Chemical Name: 8-phenoxycarbonyl-1,8-diazabicyclo[5.4.0]undec-7-enium chloride
• CAS No.: 1309041-51-7
• Molecular Formula: C₁₆H₂₁N₂O₂*Cl
• Molecular Weight: 308.808
• Mol file: 1309041-51-7.mol

Synonyms:8-phenoxycarbonyl-1,8-diazabicyclo[5.4.0]undec-7-enium chloride

Chemical Property of 8-phenoxycarbonyl-1,8-diazabicyclo[5.4.0]undec-7-enium chloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 8-phenoxycarbonyl-1,8-diazabicyclo[5.4.0]undec-7-enium chloride

There total 2 articles about 8-phenoxycarbonyl-1,8-diazabicyclo[5.4.0]undec-7-enium chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

1,8-diazabicyclo[5.4.0]undec-7-ene (6674-22-2,83329-50-4) + phenyl chloroformate (1885-14-9) → 8-phenoxycarbonyl-1,8-diazabicyclo[5.4.0]undec-7-enium chloride (1309041-51-7)

Guidance literature:

In tetrahydrofuran; at 19.84 ℃; for 1h; Inert atmosphere;

DOI:10.1002/ejoc.201001725

Reference yield:

methyl 1,8-diazabicyclo[5.4.0]undec-6-ene-8-carboxylate (1309041-52-8) → 8-phenoxycarbonyl-1,8-diazabicyclo[5.4.0]undec-7-enium chloride (1309041-51-7)

Guidance literature:

Multi-step reaction with 2 steps

1: chloroform-d1 / 16 h / 19.84 °C / Inert atmosphere

2: tetrahydrofuran / 1 h / 19.84 °C / Inert atmosphere

In tetrahydrofuran; chloroform-d1;

DOI:10.1002/ejoc.201001725

Reference yield:

methanol (67-56-1) + 8-phenoxycarbonyl-1,8-diazabicyclo[5.4.0]undec-7-enium chloride (1309041-51-7) → methyl phenyl carbonate (13509-27-8) + 1,8-diazabicyclo<5.4.0>undec-7-ene hidrochloride (78204-84-9)

Guidance literature:

With 1,8-diazabicyclo[5.4.0]undec-7-ene; In chloroform-d1; at 19.84 ℃; for 1h; Inert atmosphere;

DOI:10.1002/ejoc.201001725

upstream raw materials:

methyl 1,8-diazabicyclo[5.4.0]undec-6-ene-8-carboxylate

1,8-diazabicyclo[5.4.0]undec-7-ene

phenyl chloroformate

Downstream raw materials:

methyl phenyl carbonate

1,8-diazabicyclo<5.4.0>undec-7-ene hidrochloride

phenyl 1,8-diazabicyclo[5.4.0]undec-6-ene-8-carboxylate