2-(3,4-Dimethoxyphenyl)-2-methylpropanoic acid

Base Information

Chemical Name:2-(3,4-Dimethoxyphenyl)-2-methylpropanoic acid
CAS No.:59212-11-2
Molecular Formula:C₁₂H₁₆O₄
Molecular Weight:224.257
Hs Code.:
DSSTox Substance ID:DTXSID20482824
Wikidata:Q82319638

Synonyms:2-(3,4-DIMETHOXYPHENYL)-2-METHYLPROPANOIC ACID;59212-11-2;MFCD11036939;SCHEMBL602723;DTXSID20482824;FUSMQKBNNJVGSB-UHFFFAOYSA-N;AKOS010214371;NS-02777;CS-0453958;EN300-106056;2-(3,4-DIMETHOXYPHENYL)-2-METHYLPROPANOICACID;Z725146384

Suppliers and Price of 2-(3,4-Dimethoxyphenyl)-2-methylpropanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-(3,4-dimethoxyphenyl)-2-methylpropanoicAcid
10mg
$ 45.00

Crysdot
2-(3,4-Dimethoxyphenyl)-2-methylpropanoicacid 95+%
5g
$ 1363.00

Crysdot
2-(3,4-Dimethoxyphenyl)-2-methylpropanoicacid 95+%
1g
$ 453.00

Alichem
2-(3,4-Dimethoxyphenyl)-2-methylpropanoicacid
250mg
$ 270.32

Alichem
2-(3,4-Dimethoxyphenyl)-2-methylpropanoicacid
1g
$ 649.95

AK Scientific
2-(3,4-Dimethoxyphenyl)-2-methylpropanoicacid
5g
$ 895.00

AK Scientific
2-(3,4-Dimethoxyphenyl)-2-methylpropanoicacid
2.5g
$ 502.00

AK Scientific
2-(3,4-Dimethoxyphenyl)-2-methylpropanoicacid
500mg
$ 272.00

AK Scientific
2-(3,4-Dimethoxyphenyl)-2-methylpropanoicacid
250mg
$ 252.00

Total 4 raw suppliers

Chemical Property of 2-(3,4-Dimethoxyphenyl)-2-methylpropanoic acid

Chemical Property:

XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:224.10485899
Heavy Atom Count:16
Complexity:249

Purity/Quality:

99% ^*data from raw suppliers

2-(3,4-dimethoxyphenyl)-2-methylpropanoicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)(C1=CC(=C(C=C1)OC)OC)C(=O)O

Technology Process of 2-(3,4-Dimethoxyphenyl)-2-methylpropanoic acid

There total 3 articles about 2-(3,4-Dimethoxyphenyl)-2-methylpropanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 23023-16-7
2‐(3,4‐dimethoxyphenyl)‐2‐methylpropionitrile

: 59212-11-2
2-(3,4-dimethoxyphenyl)-2-methylpropanoic acid

Guidance literature:: With sulfuric acid; water; for 7h; Reflux;

Reference yield:

: 93-17-4
3,4-dimethoxyphenylacetonitrile

: 59212-11-2
2-(3,4-dimethoxyphenyl)-2-methylpropanoic acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydride / tetrahydrofuran / 0.17 h / 0 °C

1.2: 20 - 60 °C

2.1: sodium hydroxide / water / 24 h / Reflux

With sodium hydride; sodium hydroxide; In tetrahydrofuran; water;
DOI:10.1021/acs.jmedchem.9b00751