2-(N,N-DIMETHYLCARBOXAMIDO)PHENYLBORONIC ACID PINACOL ESTER

Base Information

• Chemical Name: 2-(N,N-DIMETHYLCARBOXAMIDO)PHENYLBORONIC ACID PINACOL ESTER
• CAS No.: 956229-73-5
• Molecular Formula: C15H22 B N O3
• Molecular Weight: 275.156
• Hs Code.: 2934999090
• Mol file: 956229-73-5.mol

Synonyms:2-(N,N-DIMETHYLCARBOXAMIDO)PHENYLBORONIC ACID PINACOL ESTER

Chemical Property of 2-(N,N-DIMETHYLCARBOXAMIDO)PHENYLBORONIC ACID PINACOL ESTER

Chemical Property:

• Melting Point: 82-85 °C
• Boiling Point: 412.8±28.0 °C(Predicted)
• PKA: -1.28±0.70(Predicted)
• PSA: 38.77000
• Density: 1.06±0.1 g/cm3(Predicted)
• LogP: 1.68760
• Storage Temp.: 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

2-(N,N-Dimethylaminocarbonyl)phenylboronicacid,pinacolester ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 2-(N,N-Dimethylaminocarbonyl)phenylboronic acid, pinacol ester

Technology Process of 2-(N,N-DIMETHYLCARBOXAMIDO)PHENYLBORONIC ACID PINACOL ESTER

There total 5 articles about 2-(N,N-DIMETHYLCARBOXAMIDO)PHENYLBORONIC ACID PINACOL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

bis(pinacol)diborane (73183-34-3) + N,N-dimethylbenzamide (611-74-5) → N,N-dimethyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide (956229-73-5)

Guidance literature:

bis(pinacol)diborane; With 5-methyl-2-(thiophen-3-yl)pyridine; (1,5-cyclooctadiene)(methoxy)iridium(I) dimer; In tetrahydrofuran; at 20 ℃; for 0.0333333h; Inert atmosphere; Glovebox;

N,N-dimethylbenzamide; In tetrahydrofuran; at 100 ℃; for 12h; regioselective reaction; Inert atmosphere; Sealed tube;

DOI:10.1021/jacs.0c13415

Reference yield: 25.0%

bis(pinacol)diborane (73183-34-3) + N,N-dimethylbenzamide (611-74-5) → N,N-dimethyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide (956229-73-5) + N,N-dimethyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide (832114-07-5) + N,N-dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide (400727-57-3)

Guidance literature:

With (1,5-cyclooctadiene)(methoxy)iridium(I) dimer; N-(2,3-dimethyl-1H-indol-7-yl)-[2,2'-bipyridine]-5-carboxamide; In tetrahydrofuran; at 50 ℃; for 24h; regioselective reaction; Inert atmosphere; Glovebox;

DOI:10.1002/anie.201907366

Reference yield:

benzoic acid (65-85-0,8013-63-6) → N,N-dimethyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide (956229-73-5)

Guidance literature:

Multi-step reaction with 3 steps

1.1: N,N-dimethyl-formamide / dichloromethane / 0.08 h / 0 °C

1.2: 4 h / 20 °C

2.1: triethylamine / dichloromethane / 12 h / 0 - 20 °C

3.1: 5-methyl-2-(thiophen-3-yl)pyridine; (1,5-cyclooctadiene)(methoxy)iridium(I) dimer / tetrahydrofuran / 0.03 h / 20 °C / Inert atmosphere; Glovebox

3.2: 12 h / 100 °C / Inert atmosphere; Sealed tube

With 5-methyl-2-(thiophen-3-yl)pyridine; (1,5-cyclooctadiene)(methoxy)iridium(I) dimer; triethylamine; N,N-dimethyl-formamide; In tetrahydrofuran; dichloromethane;

DOI:10.1021/jacs.0c13415

upstream raw materials:

N,N-dimethylbenzamide

4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane

bis(pinacol)diborane

benzoic acid

Downstream raw materials:

2,3-diphenyl-1H-inden-1-one

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 956229-73-5 2-(N,N-DIMETHYLCARBOXAMIDO)PHENYLBORONIC ACID PINACOL ESTER

Send

Send

Metric Ton KG G Pound L ML

Send

Send