(2S,3R,4R)-2-Benzyloxymethyl-3,4-bis-(tert-butyl-dimethyl-silanyloxy)-tetrahydro-furan

Base Information

Chemical Name:(2S,3R,4R)-2-Benzyloxymethyl-3,4-bis-(tert-butyl-dimethyl-silanyloxy)-tetrahydro-furan
CAS No.:191792-28-6
Molecular Formula:C₂₄H₄₄O₄Si₂
Molecular Weight:452.782
Hs Code.:

Synonyms:(2S,3R,4R)-2-Benzyloxymethyl-3,4-bis-(tert-butyl-dimethyl-silanyloxy)-tetrahydro-furan

Suppliers and Price of (2S,3R,4R)-2-Benzyloxymethyl-3,4-bis-(tert-butyl-dimethyl-silanyloxy)-tetrahydro-furan

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2S,3R,4R)-2-Benzyloxymethyl-3,4-bis-(tert-butyl-dimethyl-silanyloxy)-tetrahydro-furan

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2S,3R,4R)-2-Benzyloxymethyl-3,4-bis-(tert-butyl-dimethyl-silanyloxy)-tetrahydro-furan

There total 6 articles about (2S,3R,4R)-2-Benzyloxymethyl-3,4-bis-(tert-butyl-dimethyl-silanyloxy)-tetrahydro-furan which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 100-39-0
benzyl bromide

: 191792-27-5
[(2S,3R,4R)-3,4-Bis-(tert-butyl-dimethyl-silanyloxy)-tetrahydro-furan-2-yl]-methanol

: 191792-28-6
(2S,3R,4R)-2-Benzyloxymethyl-3,4-bis-(tert-butyl-dimethyl-silanyloxy)-tetrahydro-furan

Guidance literature:: With sodium hydride; In tetrahydrofuran; at 50 ℃; for 18h;
DOI:10.1016/S0957-4166(97)00136-5

Reference yield:

: 87-72-9,608-45-7,608-46-8,608-47-9,2460-44-8,6748-95-4,6763-34-4,7261-26-9,7283-06-9,7283-07-0,7296-55-1,7296-56-2,7296-58-4,7296-59-5,7296-60-8,7296-61-9,7296-62-0,7322-30-7,10257-31-5,10257-32-6,10257-33-7,10257-34-8,10257-35-9,19982-83-3,20242-88-0,28697-53-2,36562-42-2,41546-41-2,89299-64-9,107655-34-5,115794-06-4,115794-07-5,130550-15-1,130606-21-2
D-Xylose

: 191792-28-6
(2S,3R,4R)-2-Benzyloxymethyl-3,4-bis-(tert-butyl-dimethyl-silanyloxy)-tetrahydro-furan

Guidance literature:: Multi-step reaction with 6 steps

1: 36percent aq. HCl / 0.5 h / Ambient temperature

2: 85 percent / TsCl, pyridine / -15 °C / 1.) -15 deg C, 1.5 h, 2.) RT, 2 d

3: 95 percent / imidazole / dimethylformamide / 1.) 0 deg C, 30 min, 2.) RT, 3 d

4: 90 percent / aq. HgCl₂, HgO / acetonitrile / 1 h / Ambient temperature

5: 93 percent / 10 M BH₃*Me₂S / diethyl ether / 2 h / Ambient temperature

6: 89 percent / NaH / tetrahydrofuran / 18 h / 50 °C

With pyridine; 1H-imidazole; hydrogenchloride; dimethylsulfide borane complex; sodium hydride; p-toluenesulfonyl chloride; mercury dichloride; mercury(II) oxide; In tetrahydrofuran; diethyl ether; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1016/S0957-4166(97)00136-5

Reference yield:

: 61329-59-7
D-xylose diisobutyl dithioacetal

: 191792-28-6
(2S,3R,4R)-2-Benzyloxymethyl-3,4-bis-(tert-butyl-dimethyl-silanyloxy)-tetrahydro-furan

Guidance literature:: Multi-step reaction with 5 steps

1: 85 percent / TsCl, pyridine / -15 °C / 1.) -15 deg C, 1.5 h, 2.) RT, 2 d

2: 95 percent / imidazole / dimethylformamide / 1.) 0 deg C, 30 min, 2.) RT, 3 d

3: 90 percent / aq. HgCl₂, HgO / acetonitrile / 1 h / Ambient temperature

4: 93 percent / 10 M BH₃*Me₂S / diethyl ether / 2 h / Ambient temperature

5: 89 percent / NaH / tetrahydrofuran / 18 h / 50 °C

With pyridine; 1H-imidazole; dimethylsulfide borane complex; sodium hydride; p-toluenesulfonyl chloride; mercury dichloride; mercury(II) oxide; In tetrahydrofuran; diethyl ether; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1016/S0957-4166(97)00136-5