N-(6',6''-di-tert-butyl-18β-glycyrrhizinyl)-trans-4-aminomethylcyclohexanecarboxylic acid

Base Information

Chemical Name:N-(6',6''-di-tert-butyl-18β-glycyrrhizinyl)-trans-4-aminomethylcyclohexanecarboxylic acid
CAS No.:87919-10-6
Molecular Formula:C₅₈H₉₁NO₁₇
Molecular Weight:1074.36
Hs Code.:

Synonyms:N-(6',6''-di-tert-butyl-18β-glycyrrhizinyl)-trans-4-aminomethylcyclohexanecarboxylic acid

Suppliers and Price of N-(6',6''-di-tert-butyl-18β-glycyrrhizinyl)-trans-4-aminomethylcyclohexanecarboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-(6',6''-di-tert-butyl-18β-glycyrrhizinyl)-trans-4-aminomethylcyclohexanecarboxylic acid

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-(6',6''-di-tert-butyl-18β-glycyrrhizinyl)-trans-4-aminomethylcyclohexanecarboxylic acid

There total 7 articles about N-(6',6''-di-tert-butyl-18β-glycyrrhizinyl)-trans-4-aminomethylcyclohexanecarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.8%

: 87919-08-2
benzyl N-(6',6''-di-tert-butyl-18β-glycyrrhizinyl)-trans-4-aminomethylcyclohexanecarboxylate

: 87919-10-6
N-(6',6''-di-tert-butyl-18β-glycyrrhizinyl)-trans-4-aminomethylcyclohexanecarboxylic acid

Guidance literature:: With hydrogen; palladium on activated charcoal; In methanol; ethyl acetate; for 2.5h; under 760 Torr;

Reference yield:

: 50867-21-5
N,N'-dicylohexylcarbamimidic acid tert-butyl ester

: 87919-10-6
N-(6',6''-di-tert-butyl-18β-glycyrrhizinyl)-trans-4-aminomethylcyclohexanecarboxylic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 11.5 percent / CuCl / CHCl₃; dimethylformamide / 72 h / Ambient temperature

2: 76.3 percent / diethyl phosphorylcyanide, triethylamine / dimethylformamide / 5 degC, 1 h; 12 h, r.t.

3: 75.8 percent / hydrogen / 5percent Pd-carbon / methanol; ethyl acetate / 2.5 h / 760 Torr

With diethyl cyanophosphonate; hydrogen; triethylamine; copper(l) chloride; palladium on activated charcoal; In methanol; chloroform; ethyl acetate; N,N-dimethyl-formamide;

Reference yield:

: 83896-44-0,103000-77-7,119479-05-9,142394-43-2,1405-86-3
glycyrrizhin

: 87919-10-6
N-(6',6''-di-tert-butyl-18β-glycyrrhizinyl)-trans-4-aminomethylcyclohexanecarboxylic acid

Guidance literature:: Multi-step reaction with 6 steps

1: 22.6 percent / CHCl₃; dimethylformamide / 72 h / Ambient temperature

2: 76.5 percent / 5percent potassium hydroxide / methanol / 4 h / Ambient temperature

3: 38 percent / CuCl, dicyclohexylcarbodiimide / CHCl₃; dimethylformamide / 72 h / Ambient temperature

4: 90 percent / hydrogen / 5percent Pd-carbon / ethyl acetate / 760 Torr

5: 76.3 percent / diethyl phosphorylcyanide, triethylamine / dimethylformamide / 5 degC, 1 h; 12 h, r.t.

6: 75.8 percent / hydrogen / 5percent Pd-carbon / methanol; ethyl acetate / 2.5 h / 760 Torr

With potassium hydroxide; diethyl cyanophosphonate; hydrogen; triethylamine; dicyclohexyl-carbodiimide; copper(l) chloride; palladium on activated charcoal; In methanol; chloroform; ethyl acetate; N,N-dimethyl-formamide;