CYCLOHEXANECARBOXYLIC-D11 ACID

Base Information

• Chemical Name: CYCLOHEXANECARBOXYLIC-D11 ACID
• CAS No.: 93131-16-9
• Molecular Formula: C7H D11 O2
• Molecular Weight: 139.084
• Mol file: 93131-16-9.mol

Synonyms:CYCLOHEXANECARBOXYLIC-D11 ACID

Chemical Property of CYCLOHEXANECARBOXYLIC-D11 ACID

Chemical Property:

• PSA: 37.30000
• LogP: 1.65130
• Storage Temp.: Refrigerator
• Solubility.: Chloroform (Slightly), DMSO (Slightly)

Purity/Quality:

≥98%; ≥98% atom D ^*data from raw suppliers

Cyclohexanecarboxylic-d11 Acid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: :Cyclohexanecarboxylic-d11 Acid can be used in the synthesis of pyrazinoisoquinoline compounds as antiparasitic agents. Also used in the synthesis of benzoic anhydride and its derivatives for the synthesis of lactones. Isotope labelled Cyclohexanecarboxylic Acid used in the synthesis of pyrazinoisoquinoline compounds as antiparasitic agents. Also used in the synthesis of benzoic anhydride and its derivatives for the synthesis of lactones.

Technology Process of CYCLOHEXANECARBOXYLIC-D11 ACID

There total 2 articles about CYCLOHEXANECARBOXYLIC-D11 ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

Cyclohexanecarboxylic acid (98-89-5) → [1,2,2,3,3,4,4,5,5,6,6-2H11]cyclohexanecarboxylic acid (93131-16-9)

Guidance literature:

Cyclohexanecarboxylic acid; With d8-isopropanol; 10% Pt/activated carbon; water-d2; at 120 ℃; for 24h;

With water; sodium hydroxide; at 70 ℃; for 24h; Reagent/catalyst;

DOI:10.1002/adsc.201600363

Reference yield:

sodium benzoate (532-32-1) → [1,2,2,3,3,4,4,5,5,6,6-2H11]cyclohexanecarboxylic acid (93131-16-9)

Guidance literature:

With deuterated Raney nickel; In water-d2; for 18h; Product distribution; Heating; deuteration/reduction of aromatic nucleus;

DOI:10.1016/S0040-4039(01)81217-X

Reference yield: 99.0%

[1,2,2,3,3,4,4,5,5,6,6-2H11]cyclohexanecarboxylic acid (93131-16-9) + methyl iodide (74-88-4) → methyl cyclohexane-d11-carboxylate (1215077-49-8)

Guidance literature:

[1,2,2,3,3,4,4,5,5,6,6-2H₁₁]cyclohexanecarboxylic acid; With potassium hydroxide; In dimethyl sulfoxide; at 20 ℃; for 0.416667h;

methyl iodide; In dimethyl sulfoxide; at 20 ℃; for 20h;

upstream raw materials:

sodium benzoate

Cyclohexanecarboxylic acid

Downstream raw materials:

methyl cyclohexane-d11-carboxylate

(R)-2-(cyclohexane-d11-carbonyl)-2,3,6,7-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4(11bH)-one

2-(cyclohexane-d11-carbonyl)-2,3,6,7-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4(11bH)-one