Mebenoside, (1S)-

Base Information

Chemical Name:Mebenoside, (1S)-
CAS No.:20822-88-2
Molecular Formula:C₂₈H₃₂O₆
Molecular Weight:464.558
Hs Code.:
UNII:R17DE3X6ZV
DSSTox Substance ID:DTXSID70860072
Wikidata:Q27287650

Synonyms:Mebenoside, (1S)-;Mebenoside, (+)-;R17DE3X6ZV;UNII-R17DE3X6ZV;20822-88-2;Glucofuranoside, methyl 3,5,6-tri-o-benzyl-, alpha-D-;alpha-D-Glucofuranoside, methyl 3,5,6-tris-O-(phenylmethyl)-;(1S)-mebenoside;DTXSID70860072;Q27287650;GLUCOFURANOSIDE, METHYL 3,5,6-TRI-O-BENZYL-, .ALPHA.-D-;.ALPHA.-D-GLUCOFURANOSIDE, METHYL 3,5,6-TRIS-O-(PHENYLMETHYL)-

Suppliers and Price of Mebenoside, (1S)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Mebenoside, (1S)-

Chemical Property:

XLogP3:3.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:12
Exact Mass:464.21988874
Heavy Atom Count:34
Complexity:541

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1C(C(C(O1)C(COCC2=CC=CC=C2)OCC3=CC=CC=C3)OCC4=CC=CC=C4)O
Isomeric SMILES:CO[C@H]1[C@@H]([C@H]([C@H](O1)[C@@H](COCC2=CC=CC=C2)OCC3=CC=CC=C3)OCC4=CC=CC=C4)O

Technology Process of Mebenoside, (1S)-

There total 5 articles about Mebenoside, (1S)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 36.0%

: 67-56-1
methanol

: 53928-30-6
1,2-O-isopropylidene-3,5,6-tri-O-benzyl-α-D-glucofuranoside

: 20822-88-2
methyl 3,5,6,-tri-O-benzyl-α-D-glucofuranoside

: 20822-89-3
methyl 3,5,6,-tri-O-benzyl-β-D-glucofuranoside

Guidance literature:: With Amberlite IR-120; for 24h; Inert atmosphere; Reflux;
DOI:10.1371/journal.pone.0217712

Reference yield:

: 18549-40-1
1,2-O-isopropylidene-α-D-glucofuranose

: 20822-88-2
methyl 3,5,6,-tri-O-benzyl-α-D-glucofuranoside

Guidance literature:: Multi-step reaction with 2 steps

1: 90 percent / NaH, tetrabutylammonium iodide / dimethylformamide / 24 h / 0 °C

2: H(+) ion exchange resin / 120 h / Heating

With H(+) ion exchange resin; tetra-(n-butyl)ammonium iodide; sodium hydride; In N,N-dimethyl-formamide;
DOI:10.1016/0008-6215(84)85162-9

Reference yield:

: 100-39-0
benzyl bromide

: 20822-88-2
methyl 3,5,6,-tri-O-benzyl-α-D-glucofuranoside

Guidance literature:: Multi-step reaction with 2 steps

1: 90 percent / NaH, tetrabutylammonium iodide / dimethylformamide / 24 h / 0 °C

2: H(+) ion exchange resin / 120 h / Heating

With H(+) ion exchange resin; tetra-(n-butyl)ammonium iodide; sodium hydride; In N,N-dimethyl-formamide;
DOI:10.1016/0008-6215(84)85162-9