t-butoxycarbonyl-glycyl-glycyl-L-phenylalanyl-(Z)-α,β-dehydroleucine benzyl ester

Base Information

Chemical Name:t-butoxycarbonyl-glycyl-glycyl-L-phenylalanyl-(Z)-α,β-dehydroleucine benzyl ester
CAS No.:87067-91-2
Molecular Formula:C₃₁H₄₀N₄O₇
Molecular Weight:580.681
Hs Code.:

Synonyms:t-butoxycarbonyl-glycyl-glycyl-L-phenylalanyl-(Z)-α,β-dehydroleucine benzyl ester

Suppliers and Price of t-butoxycarbonyl-glycyl-glycyl-L-phenylalanyl-(Z)-α,β-dehydroleucine benzyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of t-butoxycarbonyl-glycyl-glycyl-L-phenylalanyl-(Z)-α,β-dehydroleucine benzyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of t-butoxycarbonyl-glycyl-glycyl-L-phenylalanyl-(Z)-α,β-dehydroleucine benzyl ester

There total 7 articles about t-butoxycarbonyl-glycyl-glycyl-L-phenylalanyl-(Z)-α,β-dehydroleucine benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 31972-52-8
Boc-Gly-Gly-OH

: 86960-62-5
H-Phe-ΔLeu-OBzl*HCl

: 87067-91-2
t-butoxycarbonyl-glycyl-glycyl-L-phenylalanyl-(Z)-α,β-dehydroleucine benzyl ester

Guidance literature:: With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In chloroform; 1.) 0 deg C, 2 h, 2.) room temperature;

Reference yield:

: 4530-20-5
BOC-glycine

: 87067-91-2
t-butoxycarbonyl-glycyl-glycyl-L-phenylalanyl-(Z)-α,β-dehydroleucine benzyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) isobutyl chloroformate, Et₃N / 1.) THF, -10 deg C, 10 min, 2.) CHCl₃, 0 deg C, 2 h; room temperature

2: 86 percent / hydrogen / 10percent palladium on carbon / methanol

3: 89 percent / Et₃N, HOBt, EDC*HCl / CHCl₃ / 1.) 0 deg C, 2 h, 2.) room temperature

With hydrogen; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; isobutyl chloroformate; palladium on activated charcoal; In methanol; chloroform;

Reference yield:

: 31972-51-7
N-(tert-butoxycarbonyl)glycylglycine benzyl ester

: 87067-91-2
t-butoxycarbonyl-glycyl-glycyl-L-phenylalanyl-(Z)-α,β-dehydroleucine benzyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 86 percent / hydrogen / 10percent palladium on carbon / methanol

2: 89 percent / Et₃N, HOBt, EDC*HCl / CHCl₃ / 1.) 0 deg C, 2 h, 2.) room temperature

With hydrogen; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; palladium on activated charcoal; In methanol; chloroform;