C₃₈H₂₈N₆O₆

Base Information

• Chemical Name: C₃₈H₂₈N₆O₆
• CAS No.: 1421318-30-0
• Molecular Formula: C₃₈H₂₈N₆O₆
• Molecular Weight: 664.677
• Mol file: 1421318-30-0.mol

Synonyms:C₃₈H₂₈N₆O₆

Chemical Property of C₃₈H₂₈N₆O₆

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₈H₂₈N₆O₆

There total 11 articles about C₃₈H₂₈N₆O₆ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

5-(4-azidobenzoylamino)-N-{2-[2-((3-(pyren-1-yl)prop-2-ynyl)oxy)acetylamino]-ethyl}isophthalamic acid methyl ester (1421318-29-7) → C38H28N6O6 (1421318-30-0)

Guidance literature:

With sodium hydroxide; In methanol; at 50 ℃; for 6h;

Reference yield:

4-azidobenzoic acid (6427-66-3) → C38H28N6O6 (1421318-30-0)

Guidance literature:

Multi-step reaction with 6 steps

1.1: (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / dichloromethane / 24 h / Reflux

2.1: sodium hydroxide / methanol / 3 h / 50 °C

3.1: (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / dichloromethane; N,N-dimethyl-formamide / 0.08 h

3.2: 48 h / 40 °C

4.1: trifluoroacetic acid / dichloromethane / 1 h / 0 - 20 °C

5.1: (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / dichloromethane; N,N-dimethyl-formamide / 20 h

6.1: sodium hydroxide / methanol / 6 h / 50 °C

With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; sodium hydroxide; In methanol; dichloromethane; N,N-dimethyl-formamide;

DOI:10.1039/c3cc38251f

Reference yield:

5-(4-azidobenzoylamino)isophthalic acid dimethyl ester (1421318-26-4) → C38H28N6O6 (1421318-30-0)

Guidance literature:

Multi-step reaction with 5 steps

1.1: sodium hydroxide / methanol / 3 h / 50 °C

2.1: (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / dichloromethane; N,N-dimethyl-formamide / 0.08 h

2.2: 48 h / 40 °C

3.1: trifluoroacetic acid / dichloromethane / 1 h / 0 - 20 °C

4.1: (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / dichloromethane; N,N-dimethyl-formamide / 20 h

5.1: sodium hydroxide / methanol / 6 h / 50 °C

With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; sodium hydroxide; In methanol; dichloromethane; N,N-dimethyl-formamide;

DOI:10.1039/c3cc38251f

upstream raw materials:

(3-pyren-1-yl-prop-2-ynyloxy)acetic acid

4-azidobenzoic acid

5-(4-azidobenzoylamino)isophthalic acid dimethyl ester

dimethyl 5-aminoisophthalate

Downstream raw materials:

5-(4-azidobenzoylamino)-N-{2-[2-((3-(pyren-1-yl)prop-2-ynyl)oxy)acetylamino]-ethyl}-N'-(4-sulfamoylbenzyl)isophthalamide

5-(4-azidobenzoylamino)-N-{2-[2-((3-(pyren-1-yl)prop-2-ynyl)oxy)acetylamino]-ethyl}isophthalamic acid (4-sulfamoylphenylcarbamoyl)methyl ester