dibenzyl-[2-(6'-bromo-[2,2']bipyridinyl-5-ylmethoxy)-1,1-bis-(6'-bromo-[2,2']bipyridinyl-5-ylmethoxymethyl)-ethyl]-amine

Base Information

• Chemical Name: dibenzyl-[2-(6'-bromo-[2,2']bipyridinyl-5-ylmethoxy)-1,1-bis-(6'-bromo-[2,2']bipyridinyl-5-ylmethoxymethyl)-ethyl]-amine
• CAS No.: 882426-58-6
• Molecular Formula: C₅₁H₄₄Br₃N₇O₃
• Molecular Weight: 1042.67
• Mol file: 882426-58-6.mol

Synonyms:dibenzyl-[2-(6'-bromo-[2,2']bipyridinyl-5-ylmethoxy)-1,1-bis-(6'-bromo-[2,2']bipyridinyl-5-ylmethoxymethyl)-ethyl]-amine

Chemical Property of dibenzyl-[2-(6'-bromo-[2,2']bipyridinyl-5-ylmethoxy)-1,1-bis-(6'-bromo-[2,2']bipyridinyl-5-ylmethoxymethyl)-ethyl]-amine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of dibenzyl-[2-(6'-bromo-[2,2']bipyridinyl-5-ylmethoxy)-1,1-bis-(6'-bromo-[2,2']bipyridinyl-5-ylmethoxymethyl)-ethyl]-amine

There total 2 articles about dibenzyl-[2-(6'-bromo-[2,2']bipyridinyl-5-ylmethoxy)-1,1-bis-(6'-bromo-[2,2']bipyridinyl-5-ylmethoxymethyl)-ethyl]-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

N,N-dibenzyl tris(hydroxymethyl)aminomethane (175724-27-3) + 6-bromo-5'-bromomethyl-2,2'-bipyridine (334001-82-0) → dibenzyl-[2-(6'-bromo-[2,2']bipyridinyl-5-ylmethoxy)-1,1-bis-(6'-bromo-[2,2']bipyridinyl-5-ylmethoxymethyl)-ethyl]-amine (882426-58-6)

Guidance literature:

With tetra-(n-butyl)ammonium iodide; sodium hydride; In N,N-dimethyl-formamide; at 25 ℃; for 19h;

DOI:10.1016/j.tetlet.2006.01.026

Reference yield:

benzyl bromide (100-39-0) → dibenzyl-[2-(6'-bromo-[2,2']bipyridinyl-5-ylmethoxy)-1,1-bis-(6'-bromo-[2,2']bipyridinyl-5-ylmethoxymethyl)-ethyl]-amine (882426-58-6)

Guidance literature:

Multi-step reaction with 2 steps

1: NaHCO₃; TBAI / H₂O / 30 h / 100 °C

2: 19 percent / NaH / dimethylformamide / 24 h / 70 °C

With tetra-(n-butyl)ammonium iodide; sodium hydride; sodium hydrogencarbonate; In water; N,N-dimethyl-formamide;

DOI:10.1016/j.tetlet.2006.01.026

Reference yield: 81.0%

dibenzyl-[2-(6'-bromo-[2,2']bipyridinyl-5-ylmethoxy)-1,1-bis-(6'-bromo-[2,2']bipyridinyl-5-ylmethoxymethyl)-ethyl]-amine (882426-58-6) + ethanol (64-17-5) + carbon monoxide (201230-82-2) → C60H59N7O9 (882426-59-7)

Guidance literature:

With bis-triphenylphosphine-palladium(II) chloride; triethylamine; In dichloromethane; at 70 ℃; under 760 Torr;

DOI:10.1016/j.tetlet.2006.01.026

upstream raw materials:

N,N-dibenzyl tris(hydroxymethyl)aminomethane

6-bromo-5'-bromomethyl-2,2'-bipyridine

benzyl bromide

Downstream raw materials:

C₆₀H₅₉N₇O₉