N,N-dibenzyl tris(hydroxymethyl)aminomethane

Base Information

• Chemical Name: N,N-dibenzyl tris(hydroxymethyl)aminomethane
• CAS No.: 175724-27-3
• Molecular Formula: C₁₈H₂₃NO₃
• Molecular Weight: 301.386
• Mol file: 175724-27-3.mol

Synonyms:N,N-dibenzyl tris(hydroxymethyl)aminomethane

Chemical Property of N,N-dibenzyl tris(hydroxymethyl)aminomethane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N,N-dibenzyl tris(hydroxymethyl)aminomethane

There total 1 articles about N,N-dibenzyl tris(hydroxymethyl)aminomethane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

benzyl bromide (100-39-0) + 2-amino-2-hydroxymethyl-1,3-propanediol (77-86-1) → N,N-dibenzyl tris(hydroxymethyl)aminomethane (175724-27-3)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; for 24h; Reflux;

DOI:10.1021/ma300972v

Reference yield: 90.0%

oxiranyl-methanol (556-52-5) + N,N-dibenzyl tris(hydroxymethyl)aminomethane (175724-27-3) → C48H83NO23

Guidance literature:

N,N-dibenzyl tris(hydroxymethyl)aminomethane; With cesiumhydroxide monohydrate; In benzene; at 20 ℃; for 1h;

oxiranyl-methanol; In diethylene glycol dimethyl ether; at 100 ℃;

DOI:10.1021/ma300972v

Reference yield: 87.0%

N,N-dibenzyl tris(hydroxymethyl)aminomethane (175724-27-3) + 6-bromo-5'-bromomethyl-2,2'-bipyridine (334001-82-0) → dibenzyl-[2-(6'-bromo-[2,2']bipyridinyl-5-ylmethoxy)-1,1-bis-(6'-bromo-[2,2']bipyridinyl-5-ylmethoxymethyl)-ethyl]-amine (882426-58-6)

Guidance literature:

With tetra-(n-butyl)ammonium iodide; sodium hydride; In N,N-dimethyl-formamide; at 25 ℃; for 19h;

DOI:10.1016/j.tetlet.2006.01.026

upstream raw materials:

benzyl bromide

2-amino-2-hydroxymethyl-1,3-propanediol

Downstream raw materials:

3-[3-(2-Cyano-ethoxy)-2-(2-cyano-ethoxymethyl)-2-dibenzylamino-propoxy]-propionitrile

di-tert-butyl fumarate

(3-tert-butoxycarbonylmethoxy-2-tert-butoxycarbonylmethoxymethyl-2-dibenzylamino-propoxy)-acetic acid tert-butyl ester

dibenzyl-[2-(6-bromo-pyridin-2-ylmethoxy)-1,1-bis-(6-bromo-pyridin-2-ylmethoxymethyl)-ethyl]-amine