Technology Process of Methyl 4-allyl-5-(benzyloxy)-2-Methoxybenzoate
There total 7 articles about Methyl 4-allyl-5-(benzyloxy)-2-Methoxybenzoate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
(4-allyl-5-benzyloxy-2-methoxy-phenyl)-methanol;
With
manganese(IV) oxide;
In
dichloromethane;
for 10h;
methanol;
With
manganese(IV) oxide; sodium cyanide; acetic acid;
for 20h;
Further stages.;
DOI:10.1021/jo000696e
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: potassium carbonate; tetra-n-butylammonium iodide / acetone / Heating
2.1: sodium hydride / tetrahydrofuran / 0 °C
3.1: 93 percent / LiAlH4 / tetrahydrofuran / 1 h / 0 °C
4.1: 65 percent / N,N-diethylaniline / 4 h / Heating
5.1: 94 percent / tetra-n-butylammonium iodide; potassium hydroxide / dimethylformamide / 18 h
6.1: MnO2 / CH2Cl2 / 10 h
6.2: 88 percent / NaCN; acetic acid; MnO2 / 20 h
With
manganese(IV) oxide; potassium hydroxide; lithium aluminium tetrahydride; tetra-(n-butyl)ammonium iodide; sodium hydride; potassium carbonate; N,N-diethylaniline;
In
tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide; acetone;
4.1: Claisen rearrangement;
DOI:10.1021/jo000696e
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: sodium hydride / tetrahydrofuran / 0 °C
2.1: 93 percent / LiAlH4 / tetrahydrofuran / 1 h / 0 °C
3.1: 65 percent / N,N-diethylaniline / 4 h / Heating
4.1: 94 percent / tetra-n-butylammonium iodide; potassium hydroxide / dimethylformamide / 18 h
5.1: MnO2 / CH2Cl2 / 10 h
5.2: 88 percent / NaCN; acetic acid; MnO2 / 20 h
With
manganese(IV) oxide; potassium hydroxide; lithium aluminium tetrahydride; tetra-(n-butyl)ammonium iodide; sodium hydride; N,N-diethylaniline;
In
tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;
3.1: Claisen rearrangement;
DOI:10.1021/jo000696e
