Technology Process of C26H27NO5
There total 6 articles about C26H27NO5 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
(R)-N,N-dimethyl-3-(2-methyl-(4-acetoxyphenyl)oxy)-3-phenyl-1-aminopropane;
With
N-ethyl-N,N-diisopropylamine;
In
toluene;
at 50 - 65 ℃;
phenyl chloroformate;
In
toluene;
at 60 - 85 ℃;
for 3h;
With
sodium hydrogencarbonate;
In
toluene;
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: potassium iodide / ethanol / 7 h / 55 - 60 °C
1.2: pH 11 - 12
1.3: 2.5 h / 20 - 25 °C
2.1: sodium hydroxide / toluene; water / pH 11 - 12
3.1: N,N-dimethyl-formamide; oxalyl dichloride / dichloromethane / 4.5 h / 0 - 35 °C / Inert atmosphere
3.2: 10.5 h / Inert atmosphere
3.3: 12.5 h / 25 - 35 °C
4.1: 3-chloro-benzenecarboperoxoic acid; acetic acid / dichloromethane / 12 h / 25 - 35 °C
5.1: N-ethyl-N,N-diisopropylamine / toluene / 50 - 65 °C
5.2: 3 h / 60 - 85 °C
With
oxalyl dichloride; acetic acid; N-ethyl-N,N-diisopropylamine; N,N-dimethyl-formamide; 3-chloro-benzenecarboperoxoic acid; potassium iodide; sodium hydroxide;
In
ethanol; dichloromethane; water; toluene;
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: 3-chloro-benzenecarboperoxoic acid; acetic acid / dichloromethane / 12 h / 25 - 35 °C
2.1: N-ethyl-N,N-diisopropylamine / toluene / 50 - 65 °C
2.2: 3 h / 60 - 85 °C
With
acetic acid; N-ethyl-N,N-diisopropylamine; 3-chloro-benzenecarboperoxoic acid;
In
dichloromethane; toluene;
