methyl 5-[(1-tert-butoxycarbonyl-4-piperidyl)oxy]-N-(tert-butoxycarbonylsulfamoyl)-N-[(7-cyano-2-naphthyl)methyl]anthranilate

Base Information

Chemical Name:methyl 5-[(1-tert-butoxycarbonyl-4-piperidyl)oxy]-N-(tert-butoxycarbonylsulfamoyl)-N-[(7-cyano-2-naphthyl)methyl]anthranilate
CAS No.:233281-67-9
Molecular Formula:C₃₅H₄₂N₄O₉S
Molecular Weight:694.806
Hs Code.:

Synonyms:methyl 5-[(1-tert-butoxycarbonyl-4-piperidyl)oxy]-N-(tert-butoxycarbonylsulfamoyl)-N-[(7-cyano-2-naphthyl)methyl]anthranilate

Suppliers and Price of methyl 5-[(1-tert-butoxycarbonyl-4-piperidyl)oxy]-N-(tert-butoxycarbonylsulfamoyl)-N-[(7-cyano-2-naphthyl)methyl]anthranilate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl 5-[(1-tert-butoxycarbonyl-4-piperidyl)oxy]-N-(tert-butoxycarbonylsulfamoyl)-N-[(7-cyano-2-naphthyl)methyl]anthranilate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl 5-[(1-tert-butoxycarbonyl-4-piperidyl)oxy]-N-(tert-butoxycarbonylsulfamoyl)-N-[(7-cyano-2-naphthyl)methyl]anthranilate

There total 4 articles about methyl 5-[(1-tert-butoxycarbonyl-4-piperidyl)oxy]-N-(tert-butoxycarbonylsulfamoyl)-N-[(7-cyano-2-naphthyl)methyl]anthranilate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 147000-89-3
N-tert-butyloxycarbonylsulfamoyl chloride

: 179756-41-3
methyl 5-[(1-tert-butoxycarbonyl-4-piperidyl)oxy]-N-[(7-cyano-2-naphthyl)methyl]anthranilate

: 233281-67-9
methyl 5-[(1-tert-butoxycarbonyl-4-piperidyl)oxy]-N-(tert-butoxycarbonylsulfamoyl)-N-[(7-cyano-2-naphthyl)methyl]anthranilate

Guidance literature:: In pyridine; at 20 ℃; for 1h;
DOI:10.1016/S0968-0896(02)00462-5

Reference yield:

: 1882-72-0
methyl 2-amino-5-hydroxybenzoate

: 233281-67-9
methyl 5-[(1-tert-butoxycarbonyl-4-piperidyl)oxy]-N-(tert-butoxycarbonylsulfamoyl)-N-[(7-cyano-2-naphthyl)methyl]anthranilate

Guidance literature:: Multi-step reaction with 3 steps

1: 41 percent / PPh₃; DEAD / tetrahydrofuran / 96 h / 20 °C

2: 99 percent / NaB(OAc)3H / CH₂Cl₂; acetic acid / 14 h / 20 °C

3: 82 percent / pyridine / 1 h / 20 °C

With sodium tris(acetoxy)borohydride; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; pyridine; dichloromethane; acetic acid; 1: Mitsunobu condensation;
DOI:10.1016/S0968-0896(02)00462-5

Reference yield:

: 109384-19-2
t-butyl 4-hydroxy piperidine-1-carboxylate

: 233281-67-9
methyl 5-[(1-tert-butoxycarbonyl-4-piperidyl)oxy]-N-(tert-butoxycarbonylsulfamoyl)-N-[(7-cyano-2-naphthyl)methyl]anthranilate

Guidance literature:: Multi-step reaction with 3 steps

1: 41 percent / PPh₃; DEAD / tetrahydrofuran / 96 h / 20 °C

2: 99 percent / NaB(OAc)3H / CH₂Cl₂; acetic acid / 14 h / 20 °C

3: 82 percent / pyridine / 1 h / 20 °C

With sodium tris(acetoxy)borohydride; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; pyridine; dichloromethane; acetic acid; 1: Mitsunobu condensation;
DOI:10.1016/S0968-0896(02)00462-5