(3aS,6aR)-3a-[(methoxy)diphenylmethyl]-5-[(1R)-1-phenylethyl]hexahydro-1H-thieno[3,4-c]pyrrole 2,2-dioxide

Base Information

Chemical Name:(3aS,6aR)-3a-[(methoxy)diphenylmethyl]-5-[(1R)-1-phenylethyl]hexahydro-1H-thieno[3,4-c]pyrrole 2,2-dioxide
CAS No.:607405-10-7
Molecular Formula:C₂₈H₃₁NO₃S
Molecular Weight:461.625
Hs Code.:

Synonyms:(3aS,6aR)-3a-[(methoxy)diphenylmethyl]-5-[(1R)-1-phenylethyl]hexahydro-1H-thieno[3,4-c]pyrrole 2,2-dioxide

Suppliers and Price of (3aS,6aR)-3a-[(methoxy)diphenylmethyl]-5-[(1R)-1-phenylethyl]hexahydro-1H-thieno[3,4-c]pyrrole 2,2-dioxide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (3aS,6aR)-3a-[(methoxy)diphenylmethyl]-5-[(1R)-1-phenylethyl]hexahydro-1H-thieno[3,4-c]pyrrole 2,2-dioxide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (3aS,6aR)-3a-[(methoxy)diphenylmethyl]-5-[(1R)-1-phenylethyl]hexahydro-1H-thieno[3,4-c]pyrrole 2,2-dioxide

There total 5 articles about (3aS,6aR)-3a-[(methoxy)diphenylmethyl]-5-[(1R)-1-phenylethyl]hexahydro-1H-thieno[3,4-c]pyrrole 2,2-dioxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 607405-08-3
[(3aS,6aR)-2,2-dioxido-5-[(1R)-1-phenylethyl]tetrahydro-1H-thieno[3,4-c]pyrrol-3a(3H)-yl]diphenylmethanol

: 74-88-4
methyl iodide

: 607405-10-7
(3aS,6aR)-3a-[(methoxy)diphenylmethyl]-5-[(1R)-1-phenylethyl]hexahydro-1H-thieno[3,4-c]pyrrole 2,2-dioxide

Guidance literature:: With sodium hydride; In tetrahydrofuran;
DOI:10.1002/ejoc.200300172

Reference yield:

: 67488-50-0
methyl 2,5-dihydrothiophene-S,S-dioxide-3-carboxylate

: 607405-10-7
(3aS,6aR)-3a-[(methoxy)diphenylmethyl]-5-[(1R)-1-phenylethyl]hexahydro-1H-thieno[3,4-c]pyrrole 2,2-dioxide

Guidance literature:: Multi-step reaction with 3 steps

1: 35 percent / trifluoroacetic acid / CH₂Cl₂ / 0.5 h / 20 °C

2: 62 percent / tetrahydrofuran; diethyl ether / 5 h

3: 88 percent / NaH / tetrahydrofuran

With sodium hydride; trifluoroacetic acid; In tetrahydrofuran; diethyl ether; dichloromethane;
DOI:10.1002/ejoc.200300172

Reference yield:

: 133407-38-2
(R)-N-(1-phenylethyl)-N-(methoxymethyl)-N-(trimethylsilylmethyl)amine

: 607405-10-7
(3aS,6aR)-3a-[(methoxy)diphenylmethyl]-5-[(1R)-1-phenylethyl]hexahydro-1H-thieno[3,4-c]pyrrole 2,2-dioxide

Guidance literature:: Multi-step reaction with 3 steps

1: 35 percent / trifluoroacetic acid / CH₂Cl₂ / 0.5 h / 20 °C

2: 62 percent / tetrahydrofuran; diethyl ether / 5 h

3: 88 percent / NaH / tetrahydrofuran

With sodium hydride; trifluoroacetic acid; In tetrahydrofuran; diethyl ether; dichloromethane;
DOI:10.1002/ejoc.200300172