Technology Process of 5-(benzyloxy)-2-(ethoxymethyl)benzofuran
There total 6 articles about 5-(benzyloxy)-2-(ethoxymethyl)benzofuran which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
(5-(benzyloxy)benzofuran-2-yl)methanol;
With
sodium hydride;
In
N,N-dimethyl-formamide; mineral oil;
at 0 ℃;
Inert atmosphere;
ethyl bromide;
With
tetra-(n-butyl)ammonium iodide;
In
N,N-dimethyl-formamide; mineral oil;
at 20 ℃;
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: potassium carbonate / acetonitrile / Reflux
2.1: magnesium bromide ethyl etherate / benzene; diethyl ether / Inert atmosphere; Reflux
3.1: potassium carbonate / acetonitrile / 60 h / Reflux
4.1: lithium aluminium tetrahydride / tetrahydrofuran / 0.5 h / 0 - 20 °C / Inert atmosphere
5.1: sodium hydride / mineral oil; N,N-dimethyl-formamide / 0 °C / Inert atmosphere
5.2: 20 °C
With
lithium aluminium tetrahydride; sodium hydride; potassium carbonate; magnesium bromide ethyl etherate;
In
tetrahydrofuran; diethyl ether; N,N-dimethyl-formamide; acetonitrile; mineral oil; benzene;
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: potassium carbonate / acetonitrile / Reflux
2.1: magnesium bromide ethyl etherate / benzene; diethyl ether / Inert atmosphere; Reflux
3.1: potassium carbonate / acetonitrile / 60 h / Reflux
4.1: lithium aluminium tetrahydride / tetrahydrofuran / 0.5 h / 0 - 20 °C / Inert atmosphere
5.1: sodium hydride / mineral oil; N,N-dimethyl-formamide / 0 °C / Inert atmosphere
5.2: 20 °C
With
lithium aluminium tetrahydride; sodium hydride; potassium carbonate; magnesium bromide ethyl etherate;
In
tetrahydrofuran; diethyl ether; N,N-dimethyl-formamide; acetonitrile; mineral oil; benzene;
