2,4,6-Tribromo-3-chloroaniline

Base Information

• Chemical Name: 2,4,6-Tribromo-3-chloroaniline
• CAS No.: 89284-57-1
• Molecular Formula: C₆H₃Br₃ClN
• Molecular Weight: 364.262
• DSSTox Substance ID: DTXSID201023392
• Mol file: 89284-57-1.mol

Synonyms:2,4,6-Tribromo-3-chloroaniline;2.4.6-Tribrom-3-chloranilin;DTXSID201023392;89284-57-1

Chemical Property of 2,4,6-Tribromo-3-chloroaniline

Chemical Property:

• XLogP3: 3.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 362.74837
• Heavy Atom Count: 11
• Complexity: 146

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=C(C(=C(C(=C1Br)Cl)Br)N)Br

Technology Process of 2,4,6-Tribromo-3-chloroaniline

There total 7 articles about 2,4,6-Tribromo-3-chloroaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.8%

3-chloro-aniline (108-42-9) → 3-chloro-2,4,6-tribromoaniline (89284-57-1)

Guidance literature:

With hydrogenchloride; dihydrogen peroxide; sodium bromide; In water; at 15 ℃; for 2h;

DOI:10.1134/S1070427208080314

Reference yield:

bromine (7726-95-6) + acetic acid (64-19-7,77671-22-8) + 3-chloro-aniline (108-42-9) → 4-bromo-3-chloroaniline (21402-26-6) + 3-chloro-2,4,6-tribromoaniline (89284-57-1) + 2,4-dibromo-5-chloroaniline (89379-50-0)

Guidance literature:

Reference yield:

1-amino-3-chlorobenzene-6-sulfonic acid (3479-10-5) → 3-chloro-2,4,6-tribromoaniline (89284-57-1)

Guidance literature:

With water; bromine;

DOI:10.1021/jo01167a005

upstream raw materials:

1-amino-3-chlorobenzene-6-sulfonic acid

5-(3-chloro-anilino)-penta-2,4-dienal-(3-chloro-phenylimine)

3-chloro-aniline

bromine

Downstream raw materials:

1,3,5-tribromo-2-chloro-benzene