methyl (2E)-2-[2-[(1,3-dioxoisoindolin-2-yl)oxymethyl]phenyl]-2-methoxyiminoacetate

Base Information

• Chemical Name: methyl (2E)-2-[2-[(1,3-dioxoisoindolin-2-yl)oxymethyl]phenyl]-2-methoxyiminoacetate
• CAS No.: 156581-14-5
• Molecular Formula: C₁₉H₁₆N₂O₆
• Molecular Weight: 368.346
• Mol file: 156581-14-5.mol

Synonyms:methyl (2E)-2-[2-[(1,3-dioxoisoindolin-2-yl)oxymethyl]phenyl]-2-methoxyiminoacetate

Chemical Property of methyl (2E)-2-[2-[(1,3-dioxoisoindolin-2-yl)oxymethyl]phenyl]-2-methoxyiminoacetate

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl (2E)-2-[2-[(1,3-dioxoisoindolin-2-yl)oxymethyl]phenyl]-2-methoxyiminoacetate

There total 6 articles about methyl (2E)-2-[2-[(1,3-dioxoisoindolin-2-yl)oxymethyl]phenyl]-2-methoxyiminoacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

methyl 2-(2-bromomethyl)phenyl-2-methoxyiminoacetate (115199-26-3) + N-hydroxyphthalimide (524-38-9) → methyl (2E)-2-[2-[(1,3-dioxoisoindolin-2-yl)oxymethyl]phenyl]-2-methoxyiminoacetate (156581-14-5)

Guidance literature:

With sodium hydroxide; nitrogen; In N-methyl-acetamide; water;

Reference yield: 98.0%

N-hydroxyphthalimide (524-38-9) + benzyl bromide (100-39-0) → methyl (2E)-2-[2-[(1,3-dioxoisoindolin-2-yl)oxymethyl]phenyl]-2-methoxyiminoacetate (156581-14-5)

Guidance literature:

With sodium hydroxide; nitrogen; In N-methyl-acetamide; water;

Reference yield: 91.0%

N-hydroxyphthalimide (524-38-9) + methyl (E)-2-[2-(bromomethyl)phenyl]-2-(methoxyimino)acetate (133409-72-0) → methyl (2E)-2-[2-[(1,3-dioxoisoindolin-2-yl)oxymethyl]phenyl]-2-methoxyiminoacetate (156581-14-5)

Guidance literature:

N-hydroxyphthalimide; With sodium hydroxide; In N,N-dimethyl-formamide; at 20 ℃; for 0.333333h;

methyl (E)-2-[2-(bromomethyl)phenyl]-2-(methoxyimino)acetate; In N,N-dimethyl-formamide; at 20 ℃;

DOI:10.1021/jf060074f

upstream raw materials:

N-hydroxyphthalimide

methyl (E)-2-[2-(bromomethyl)phenyl]-2-(methoxyimino)acetate

methyl (E)-2-hydroxyimino-2-o-tolylacetate

methyl-(E)-2-(2-tolyl)-2-methoxyiminoacetate

Downstream raw materials:

methyl (E)-α-(methoxyimino)-2-(aminoxymethyl)benzeneacetate