1-O-tert-Butyldimethylsilyl-6-(2,4-dichlorophenyl)-D-erythro-1,2,4-hexanetriol

Base Information

• Chemical Name: 1-O-tert-Butyldimethylsilyl-6-(2,4-dichlorophenyl)-D-erythro-1,2,4-hexanetriol
• CAS No.: 141263-57-2
• Molecular Formula: C₁₈H₃₀Cl₂O₃Si
• Molecular Weight: 393.426

Synonyms:1-O-tert-Butyldimethylsilyl-6-(2,4-dichlorophenyl)-D-erythro-1,2,4-hexanetriol

Chemical Property of 1-O-tert-Butyldimethylsilyl-6-(2,4-dichlorophenyl)-D-erythro-1,2,4-hexanetriol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-O-tert-Butyldimethylsilyl-6-(2,4-dichlorophenyl)-D-erythro-1,2,4-hexanetriol

There total 2 articles about 1-O-tert-Butyldimethylsilyl-6-(2,4-dichlorophenyl)-D-erythro-1,2,4-hexanetriol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.8%

tert-butyldimethylsilyl chloride (18162-48-6) + 6-(2,4-Dichlorophenyl)-D-erythro-1,2,4-hexanetriol (141263-56-1) → 1-O-tert-Butyldimethylsilyl-6-(2,4-dichlorophenyl)-D-erythro-1,2,4-hexanetriol (141263-57-2)

Guidance literature:

With pyridine; for 3h; Ambient temperature;

DOI:10.1016/S0008-6215(00)90500-7

Reference yield:

(3R,5R)-5-[2-(2,4-Dichloro-phenyl)-ethyl]-tetrahydro-furan-2,3-diol (101910-02-5,101910-03-6,141263-55-0) → 1-O-tert-Butyldimethylsilyl-6-(2,4-dichlorophenyl)-D-erythro-1,2,4-hexanetriol (141263-57-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 95.6 percent / NaBH₄ / ethanol / 1 h / 0 °C

2: 78.8 percent / pyridine / 3 h / Ambient temperature

With pyridine; sodium tetrahydroborate; In ethanol;

DOI:10.1016/S0008-6215(00)90500-7

Reference yield: 89.5%

1-O-tert-Butyldimethylsilyl-6-(2,4-dichlorophenyl)-D-erythro-1,2,4-hexanetriol (141263-57-2) + acetone (67-64-1) → 1-O-tert-Butyldimethylsilyl-6-(2,4-dichlorophenyl)-2,4-O-isopropylidene-D-erythro-1,2,4-hexanetriol (141263-58-3)

Guidance literature:

With 2-Methoxypropene; toluene-4-sulfonic acid; at 20 ℃; for 0.666667h;

DOI:10.1016/S0008-6215(00)90500-7

upstream raw materials:

tert-butyldimethylsilyl chloride

6-(2,4-Dichlorophenyl)-D-erythro-1,2,4-hexanetriol

(3R,5R)-5-[2-(2,4-Dichloro-phenyl)-ethyl]-tetrahydro-furan-2,3-diol

Downstream raw materials:

1-O-tert-Butyldimethylsilyl-6-(2,4-dichlorophenyl)-2,4-O-isopropylidene-D-erythro-1,2,4-hexanetriol

7-(2,4-Dichlorophenyl)-D-erythro-3-hydroxy-5-heptanolide

1,4-Anhydro-6-(2,4-dichlorophenyl)-D-erythro-1,2,4-hexanetriol

6-(2,4-Dichlorophenyl)-2,4-O-isopropylidene-D-erythro-1,2,4-hexanetriol

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 141263-57-2 1-O-tert-Butyldimethylsilyl-6-(2,4-dichlorophenyl)-D-erythro-1,2,4-hexanetriol

Send

Send

Metric Ton KG G Pound L ML

Send

Send