C₃₁H₃₀N₂O₅

Base Information

• Chemical Name: C₃₁H₃₀N₂O₅
• CAS No.: 1264366-68-8
• Molecular Formula: C₃₁H₃₀N₂O₅
• Molecular Weight: 510.59
• Mol file: 1264366-68-8.mol

Synonyms:C₃₁H₃₀N₂O₅

Chemical Property of C₃₁H₃₀N₂O₅

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₁H₃₀N₂O₅

There total 4 articles about C₃₁H₃₀N₂O₅ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

glycolic Acid (79-14-1) + 2-(4-benzyloxyphenyl)ethylisocyanide (244221-02-1) + benzaldehyde (100-52-7) + 2-amino-phenol (95-55-6) → C31H30N2O5 (1264366-68-8)

Guidance literature:

In isopropyl alcohol; at 20 ℃; for 48h; Molecular sieve; Inert atmosphere;

DOI:10.1002/ejoc.201001077

Reference yield:

tyrosamine (51-67-2) → C31H30N2O5 (1264366-68-8)

Guidance literature:

Multi-step reaction with 4 steps

1: 31 h / Reflux

2: potassium carbonate / acetone / 12 h / Reflux

3: triethylamine; trichlorophosphate / dichloromethane / 2.25 h / -30 °C / Inert atmosphere

4: isopropyl alcohol / 48 h / 20 °C / Molecular sieve; Inert atmosphere

With potassium carbonate; triethylamine; trichlorophosphate; In dichloromethane; isopropyl alcohol; acetone; 4: Ugi condensation;

DOI:10.1002/ejoc.201001077

Reference yield:

N-[2-(4-hydroxyphenyl)ethyl]formamide (13062-78-7) → C31H30N2O5 (1264366-68-8)

Guidance literature:

Multi-step reaction with 3 steps

1: potassium carbonate / acetone / 12 h / Reflux

2: triethylamine; trichlorophosphate / dichloromethane / 2.25 h / -30 °C / Inert atmosphere

3: isopropyl alcohol / 48 h / 20 °C / Molecular sieve; Inert atmosphere

With potassium carbonate; triethylamine; trichlorophosphate; In dichloromethane; isopropyl alcohol; acetone; 3: Ugi condensation;

DOI:10.1002/ejoc.201001077

upstream raw materials:

tyrosamine

glycolic Acid

2-(4-benzyloxyphenyl)ethylisocyanide

benzaldehyde

Downstream raw materials:

N-{[2-(4-benzyloxy)phenyl]ethyl}-2-{3-oxo-2H-benzo[b][1,4]oxazin-4(3H)-yl}-2-phenylacetamide

N-[2-(4-hydroxyphenyl)ethyl]-2-{3-oxo-2H-benzo[b][1,4]oxazin-4(3H)-yl}-2-phenylacetamide