(R)-2-[(R)-2-(5-bromo-2-fluoro-phenyl)-2-(2-nitro-benzenesulfonylamino)-propoxy]-3,3,3-trifluoro-2-methyl-propionamide

Base Information

Chemical Name:(R)-2-[(R)-2-(5-bromo-2-fluoro-phenyl)-2-(2-nitro-benzenesulfonylamino)-propoxy]-3,3,3-trifluoro-2-methyl-propionamide
CAS No.:1262859-64-2
Molecular Formula:C₁₉H₁₈BrF₄N₃O₆S
Molecular Weight:572.332
Hs Code.:

Synonyms:(R)-2-[(R)-2-(5-bromo-2-fluoro-phenyl)-2-(2-nitro-benzenesulfonylamino)-propoxy]-3,3,3-trifluoro-2-methyl-propionamide

Suppliers and Price of (R)-2-[(R)-2-(5-bromo-2-fluoro-phenyl)-2-(2-nitro-benzenesulfonylamino)-propoxy]-3,3,3-trifluoro-2-methyl-propionamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (R)-2-[(R)-2-(5-bromo-2-fluoro-phenyl)-2-(2-nitro-benzenesulfonylamino)-propoxy]-3,3,3-trifluoro-2-methyl-propionamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (R)-2-[(R)-2-(5-bromo-2-fluoro-phenyl)-2-(2-nitro-benzenesulfonylamino)-propoxy]-3,3,3-trifluoro-2-methyl-propionamide

There total 13 articles about (R)-2-[(R)-2-(5-bromo-2-fluoro-phenyl)-2-(2-nitro-benzenesulfonylamino)-propoxy]-3,3,3-trifluoro-2-methyl-propionamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1262859-63-1
(R)-2-[(R)-2-(5-bromo-2-fluoro-phenyl)-2-(2-nitro-benzenesulfonylamino)-propoxy]-3,3,3-trifluoro-2-methyl-propionic acid ethyl ester

: 1262859-64-2
(R)-2-[(R)-2-(5-bromo-2-fluoro-phenyl)-2-(2-nitro-benzenesulfonylamino)-propoxy]-3,3,3-trifluoro-2-methyl-propionamide

Guidance literature:: With ammonia; In methanol; at 50 ℃; for 16h;

Reference yield:

: (R)-2-[(R)-2-(5-bromo-2-fluorophenyl)-2-(2-nitrobenzenesulfonylamino)propoxy]-3,3,3-trifluoro-2-methylpropionic acid ethyl ester

: 1262859-64-2
(R)-2-[(R)-2-(5-bromo-2-fluoro-phenyl)-2-(2-nitro-benzenesulfonylamino)-propoxy]-3,3,3-trifluoro-2-methyl-propionamide

Guidance literature:: With ammonia; In methanol; at 50 ℃; for 16h;

Reference yield:

: 460-00-4
1-Bromo-4-fluorobenzene

: 1262859-64-2
(R)-2-[(R)-2-(5-bromo-2-fluoro-phenyl)-2-(2-nitro-benzenesulfonylamino)-propoxy]-3,3,3-trifluoro-2-methyl-propionamide

Guidance literature:: Multi-step reaction with 10 steps

1: n-butyllithium / hexane; tetrahydrofuran; acetone

2: phosphoric acid / dichloromethane; hexane

3: potassium carbonate; K₃Fe(CN)6; Na₂S₂O₅ / K₂OsO₂(OH)4 / t-BuOH-H₂O

4: hydrogenchloride; sodium hydroxide / dichloromethane

5: ammonium chloride; sodium azide / ethanol

6: NaOH; LiAlH₄ / water; tetrahydrofuran

7: sodium hydroxide / tetrahydrofuran

8: triphenylphosphine / dichloromethane

9: hydrogenchloride; NaH / N,N-dimethyl-formamide; mineral oil

10: ammonia; methanol

With hydrogenchloride; sodium hydroxide; NaOH; n-butyllithium; sodium azide; LiAlH₄; K₃Fe(CN)6; Na₂S₂O₅; NaH; phosphoric acid; ammonium chloride; potassium carbonate; triphenylphosphine; K₂OsO₂(OH)4; In tetrahydrofuran; methanol; ethanol; hexane; dichloromethane; t-BuOH-H₂O; ammonia; water; N,N-dimethyl-formamide; acetone; mineral oil;