3,4-bis(4-methoxyphenyl)-1-[2-(4-methoxyphenyl)ethyl]pyrrole-2,5-dicarboxylic acid

Base Information

• Chemical Name: 3,4-bis(4-methoxyphenyl)-1-[2-(4-methoxyphenyl)ethyl]pyrrole-2,5-dicarboxylic acid
• CAS No.: 917479-37-9
• Molecular Formula: C₂₉H₂₇NO₇
• Molecular Weight: 501.536
• Mol file: 917479-37-9.mol

Synonyms:3,4-bis(4-methoxyphenyl)-1-[2-(4-methoxyphenyl)ethyl]pyrrole-2,5-dicarboxylic acid

Chemical Property of 3,4-bis(4-methoxyphenyl)-1-[2-(4-methoxyphenyl)ethyl]pyrrole-2,5-dicarboxylic acid

Chemical Property:

Purity/Quality:

Safty Information:

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• Hazard Codes: 

MSDS Files:

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Technology Process of 3,4-bis(4-methoxyphenyl)-1-[2-(4-methoxyphenyl)ethyl]pyrrole-2,5-dicarboxylic acid

There total 1 articles about 3,4-bis(4-methoxyphenyl)-1-[2-(4-methoxyphenyl)ethyl]pyrrole-2,5-dicarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

3-(4-methoxyphenyl)-2-oxopropanoic acid (28030-16-2) + 4-Methoxyphenethylamine (55-81-2) → 3,4-bis(4-methoxyphenyl)-1-[2-(4-methoxyphenyl)ethyl]pyrrole-2,5-dicarboxylic acid (917479-37-9)

Guidance literature:

3-(4-methoxyphenyl)-2-oxopropanoic acid; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 0.333333h;

4-Methoxyphenethylamine; With 4 A molecular sieve; iodine; In tetrahydrofuran; hexane; at 20 ℃; for 19h; Further stages.;

DOI:10.1055/s-2006-950190

Reference yield: 100.0%

3,4-bis(4-methoxyphenyl)-1-[2-(4-methoxyphenyl)ethyl]pyrrole-2,5-dicarboxylic acid (917479-37-9) → 3,4-bis(4-methoxyphenyl)-1-[2-(4-methoxyphenyl)ethyl]pyrrole-2,5-dione

Guidance literature:

With bromine; In methanol; Heating;

DOI:10.1055/s-2006-950190

Reference yield: 94.0%

3,4-bis(4-methoxyphenyl)-1-[2-(4-methoxyphenyl)ethyl]pyrrole-2,5-dicarboxylic acid (917479-37-9) + methyl iodide (74-88-4) → 3,4-bis(4-methoxyphenyl)-1-[2-(4-methoxyphenyl)ethyl]pyrrole-2,5-dicarboxylic acid dimethyl ester (570402-59-4)

Guidance literature:

With 1,8-diazabicyclo[5.4.0]undec-7-ene; In N,N-dimethyl-formamide; at 20 ℃; for 18h;

DOI:10.1055/s-2006-950190

upstream raw materials:

3-(4-methoxyphenyl)-2-oxopropanoic acid

4-Methoxyphenethylamine

Downstream raw materials:

3,4-bis(4-methoxyphenyl)-1-[2-(4-methoxyphenyl)ethyl]pyrrole-2,5-dicarboxylic acid dimethyl ester

{5-(4-methoxybenzoyl)-3,4-bis(4-methoxyphenyl)-1-[2-(4-methoxyphenyl)ethyl]-1H-pyrrol-2-yl}-(4-methoxyphenyl)methanone