(2S,3S)-cis-1-(N-1-bis(4-methoxy-3,5-dimethyllphenyl)methyl)-2-carboxyethyl-3-phenylaziridine

Base Information

Chemical Name:(2S,3S)-cis-1-(N-1-bis(4-methoxy-3,5-dimethyllphenyl)methyl)-2-carboxyethyl-3-phenylaziridine
CAS No.:1072879-81-2
Molecular Formula:C₃₀H₃₅NO₄
Molecular Weight:473.612
Hs Code.:

Synonyms:(2S,3S)-cis-1-(N-1-bis(4-methoxy-3,5-dimethyllphenyl)methyl)-2-carboxyethyl-3-phenylaziridine

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Chemical Property of (2S,3S)-cis-1-(N-1-bis(4-methoxy-3,5-dimethyllphenyl)methyl)-2-carboxyethyl-3-phenylaziridine

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Technology Process of (2S,3S)-cis-1-(N-1-bis(4-methoxy-3,5-dimethyllphenyl)methyl)-2-carboxyethyl-3-phenylaziridine

There total 12 articles about (2S,3S)-cis-1-(N-1-bis(4-methoxy-3,5-dimethyllphenyl)methyl)-2-carboxyethyl-3-phenylaziridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 623-73-4
diazoacetic acid ethyl ester

: 1072879-54-9
3,3',5,5'-tetramethyl-4,4'-dimethoxy benzhydrylamine

: 100-52-7
benzaldehyde

: 1072879-81-2
(2S,3S)-cis-1-(N-1-bis(4-methoxy-3,5-dimethyllphenyl)methyl)-2-carboxyethyl-3-phenylaziridine

Guidance literature:: 3,3',5,5'-tetramethyl-4,4'-dimethoxy benzhydrylamine; With triphenylborane; (R)-t-Bu₂VANOL; In toluene; at 80 ℃; for 0.5h; Inert atmosphere; Schlenk technique;

diazoacetic acid ethyl ester; benzaldehyde; In toluene; at 25 ℃; for 24h; enantioselective reaction; Molecular sieve; Inert atmosphere; Schlenk technique;
DOI:10.1002/ejoc.201301766

Reference yield: 98.0%

: 623-73-4
diazoacetic acid ethyl ester

: 1072879-63-0
N-phenylmethylidene-1,1-bis(4-methoxy-3,5-dimethylphenyl)methylamine

: 1072879-81-2
(2S,3S)-cis-1-(N-1-bis(4-methoxy-3,5-dimethyllphenyl)methyl)-2-carboxyethyl-3-phenylaziridine

Guidance literature:: With (2R)-(+)-3,3'-diphenyl-[2,2'-dinaphthalene]-1,1'-diol; In toluene; at 25 ℃; for 24h; enantioselective reaction;
DOI:10.1039/c4cy00742e