N-phenylmethylidene-1,1-bis(4-methoxy-3,5-dimethylphenyl)methylamine

Base Information

• Chemical Name: N-phenylmethylidene-1,1-bis(4-methoxy-3,5-dimethylphenyl)methylamine
• CAS No.: 1072879-63-0
• Molecular Formula: C₂₆H₂₉NO₂
• Molecular Weight: 387.522
• Mol file: 1072879-63-0.mol

Synonyms:N-phenylmethylidene-1,1-bis(4-methoxy-3,5-dimethylphenyl)methylamine

Chemical Property of N-phenylmethylidene-1,1-bis(4-methoxy-3,5-dimethylphenyl)methylamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of N-phenylmethylidene-1,1-bis(4-methoxy-3,5-dimethylphenyl)methylamine

There total 4 articles about N-phenylmethylidene-1,1-bis(4-methoxy-3,5-dimethylphenyl)methylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

3,3',5,5'-tetramethyl-4,4'-dimethoxy benzhydrylamine (1072879-54-9) + benzaldehyde (100-52-7) → N-phenylmethylidene-1,1-bis(4-methoxy-3,5-dimethylphenyl)methylamine (1072879-63-0)

Guidance literature:

With magnesium sulfate; In dichloromethane; at 25 ℃; for 24h; Inert atmosphere;

DOI:10.1021/ja1070224

Reference yield: 90.0%

bis-(2,6-di-methyl-4-methoxyphenyl)methineamine + benzaldehyde (100-52-7) → N-phenylmethylidene-1,1-bis(4-methoxy-3,5-dimethylphenyl)methylamine (1072879-63-0)

Guidance literature:

With magnesium sulfate; In dichloromethane; at 25 ℃; for 24h; Inert atmosphere;

DOI:10.1021/jo101160c

Reference yield:

diazoacetic acid ethyl ester (623-73-4) + 3,3',5,5'-tetramethyl-4,4'-dimethoxy benzhydrylamine (1072879-54-9) + benzaldehyde (100-52-7) → N-phenylmethylidene-1,1-bis(4-methoxy-3,5-dimethylphenyl)methylamine (1072879-63-0) + ethyl 3-oxo-3-phenylpropionate (94-02-0)

Guidance literature:

With triphenylborane; (3S)-(+)-2,2'-diphenyl-(3,3'-biphenanthrene)-4,4'-diol; In chloroform-d1; at 25 ℃; for 24h; Molecular sieve; Inert atmosphere;

DOI:10.1021/jo301064u

upstream raw materials:

3,3',5,5'-tetramethyl-4,4'-dimethoxy benzhydrylamine

benzaldehyde

diazoacetic acid ethyl ester

Downstream raw materials:

(2R,3R)-cis-1-(N-1-bis(4-methoxy-3,5-dimethylphenyl)methyl)-2-carboxyethyl-3-phenylaziridine

(2S,3S)-cis-1-(N-1-bis(4-methoxy-3,5-dimethyllphenyl)methyl)-2-carboxyethyl-3-phenylaziridine

(2S,3S)-N-benzyl-1-(bis(4-methoxy-3,5-dimethylphenyl)methyl)-N-methyl-3-phenylaziridine-2-carboxamide

(2R,3R)-N-benzyl-1-(bis(4-methoxy-3,5-dimethylphenyl)methyl)-N-methyl-3-phenylaziridine-2-carboxamide