Technology Process of 2-(3-chlorophenyl)acrylic acid
There total 6 articles about 2-(3-chlorophenyl)acrylic acid which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
bis(acetylacetonate)nickel(II); (R,R)-(+)-1,2-bis(t-butylmethylphosphino)benzene; acetic anhydride;
In
tetrahydrofuran;
at 100 ℃;
for 5h;
regioselective reaction;
Autoclave;
Glovebox;
Inert atmosphere;
DOI:10.1039/c6gc00549g
- Guidance literature:
-
With
bis(acetylacetonate)nickel(II); (R,R)-(+)-1,2-bis(t-butylmethylphosphino)benzene; acetic anhydride;
In
tetrahydrofuran;
at 100 ℃;
for 5h;
Green chemistry;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: potassium carbonate; tetra-(n-butyl)ammonium iodide / toluene / 12 h / 50 °C
2: sodium hydroxide / 2 h / Reflux
With
tetra-(n-butyl)ammonium iodide; potassium carbonate; sodium hydroxide;
In
toluene;
DOI:10.1002/anie.201700195
