3,3-dichloro-1-(4-methoxy-phenyl)-2-(2,4,6-trifluoro-phenyl)-propenone

Base Information

Chemical Name:3,3-dichloro-1-(4-methoxy-phenyl)-2-(2,4,6-trifluoro-phenyl)-propenone
CAS No.:1192118-92-5
Molecular Formula:C₁₆H₉Cl₂F₃O₂
Molecular Weight:361.147
Hs Code.:

Synonyms:3,3-dichloro-1-(4-methoxy-phenyl)-2-(2,4,6-trifluoro-phenyl)-propenone

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3,3-dichloro-1-(4-methoxy-phenyl)-2-(2,4,6-trifluoro-phenyl)-propenone

Chemical Property:

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Technology Process of 3,3-dichloro-1-(4-methoxy-phenyl)-2-(2,4,6-trifluoro-phenyl)-propenone

There total 5 articles about 3,3-dichloro-1-(4-methoxy-phenyl)-2-(2,4,6-trifluoro-phenyl)-propenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

: 1020662-71-8
3,3-dichloro-2-(2,4,6-trifluorophenyl)acryloyl chloride

: 100-66-3
methoxybenzene

: 1192118-92-5
3,3-dichloro-1-(4-methoxy-phenyl)-2-(2,4,6-trifluoro-phenyl)-propenone

Guidance literature:: With aluminum (III) chloride;
DOI:10.1055/s-0033-1338433

Reference yield:

: 2367-76-2
2,4,6-trifluorobromobenzene

: 1192118-92-5
3,3-dichloro-1-(4-methoxy-phenyl)-2-(2,4,6-trifluoro-phenyl)-propenone

Guidance literature:: Multi-step reaction with 4 steps

1: isopropylmagnesium chloride

2: triphenylphosphine

3: potassium hydroxide

4: aluminum (III) chloride

With aluminum (III) chloride; isopropylmagnesium chloride; triphenylphosphine; potassium hydroxide; 2: |Corey-Fuchs Alkyne Synthesis / 4: |Friedel-Crafts Acylation;
DOI:10.1055/s-0033-1338433

Reference yield:

: 918418-99-2
ethyl 2,4,6-trifluorophenylglyoxylate

: 1192118-92-5
3,3-dichloro-1-(4-methoxy-phenyl)-2-(2,4,6-trifluoro-phenyl)-propenone

Guidance literature:: Multi-step reaction with 3 steps

1: triphenylphosphine

2: potassium hydroxide

3: aluminum (III) chloride

With aluminum (III) chloride; triphenylphosphine; potassium hydroxide; 1: |Corey-Fuchs Alkyne Synthesis / 3: |Friedel-Crafts Acylation;
DOI:10.1055/s-0033-1338433