1-benzyl-3-(2-bromoethyl)-1H-imidazol-3-ium bromide

Base Information

• Chemical Name: 1-benzyl-3-(2-bromoethyl)-1H-imidazol-3-ium bromide
• CAS No.: 1333403-17-0
• Molecular Formula: Br*C₁₂H₁₄BrN₂
• Molecular Weight: 346.065
• Mol file: 1333403-17-0.mol

Synonyms:1-benzyl-3-(2-bromoethyl)-1H-imidazol-3-ium bromide

Chemical Property of 1-benzyl-3-(2-bromoethyl)-1H-imidazol-3-ium bromide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-benzyl-3-(2-bromoethyl)-1H-imidazol-3-ium bromide

There total 3 articles about 1-benzyl-3-(2-bromoethyl)-1H-imidazol-3-ium bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

1-benzylimidazole (4238-71-5) + ethylene dibromide (106-93-4) → 1-benzyl-3-(2-bromoethyl)-1H-imidazol-3-ium bromide (1333403-17-0)

Guidance literature:

at 85 ℃; for 16h; Schlenk technique; Inert atmosphere;

DOI:10.1002/ejic.201701183

Reference yield: 80.0%

1-benzylimidazole (4238-71-5) + ethylene dibromide (106-93-4) → 1-benzyl-3-(2-bromoethyl)-1H-imidazol-3-ium bromide (1333403-17-0) + 1,1′-bis(benzyl)-3,3′-(ethane-1,2-diyl)diimidazolium dibromide

Guidance literature:

In acetonitrile; at 100 ℃; for 12h; Inert atmosphere;

DOI:10.1039/c9dt01362h

Reference yield:

benzyl bromide (100-39-0) → 1-benzyl-3-(2-bromoethyl)-1H-imidazol-3-ium bromide (1333403-17-0)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium hydroxide / water / 0.5 h / 20 °C

2: 85 °C

With sodium hydroxide; In water;

DOI:10.1039/c1dt10269a

upstream raw materials:

1-benzylimidazole

ethylene dibromide

benzyl bromide

Refernces

• 1、 Karmis, Rebecca E.,Carrara, Serena,Baxter, Amy A.,Hogan, Conor F.,Hulett, Mark D.,Barnard, Peter J.. "Luminescent iridium(iii) complexes of N-heterocyclic carbene ligands prepared using the 'click reaction'". . p. 9998 - 10010. Retrieved 2019.
• 2、 Banerjee, Kaustav,Bhattacherjee, Debojit,Mahato, Sulendar K.,Sufian, Abu,Bhabak, Krishna Pada. "Benzimidazole- And Imidazole-Fused Selenazolium and Selenazinium Selenocyanates: Ionic Organoselenium Compounds with Efficient Peroxide Scavenging Activities". . p. 12984 - 12999. Retrieved 2021/08/30.