[2-(4-Methoxyphenyl)-1,3-thiazol-4-yl]methanol

Base Information

Chemical Name:[2-(4-Methoxyphenyl)-1,3-thiazol-4-yl]methanol
CAS No.:885279-75-4
Molecular Formula:C11H11 N O2 S
Molecular Weight:221.28
Hs Code.:2934100090
DSSTox Substance ID:DTXSID70586184
Wikidata:Q82478259
Mol file:885279-75-4.mol

Synonyms:885279-75-4;[2-(4-Methoxyphenyl)-1,3-thiazol-4-yl]methanol;(2-(4-Methoxyphenyl)thiazol-4-yl)methanol;[2-(4-METHOXY-PHENYL)-THIAZOL-4-YL]-METHANOL;MFCD06738392;[2-(4-methoxyphenyl)thiazol-4-yl]methanol;SCHEMBL202826;DTXSID70586184;VFSRWAISOVFLJP-UHFFFAOYSA-N;STL451492;AKOS000126466;AB27072;MCULE-6151065867;DB-077817;CS-0131335;EN300-96144;G37843;11Z-0702;J-500520;(2-(4-Methoxyphenyl)thiazol-4-yl)methanol, AldrichCPR;Z228585892;[2-(4-methoxyphenyl)-1,3-thiazol-4-yl]methanol, AldrichCPR

Suppliers and Price of [2-(4-Methoxyphenyl)-1,3-thiazol-4-yl]methanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
[2-(4-methoxyphenyl)-1,3-thiazol-4-yl]methanol
5mg
$ 45.00

SynQuest Laboratories
4-(Hydroxymethyl)-2-(4-methoxyphenyl)-1,3-thiazole
500 mg
$ 295.00

Sigma-Aldrich
(2-(4-Methoxyphenyl)thiazol-4-yl)methanol Aldrich
1g
$ 554.00

Matrix Scientific
[2-(4-Methoxyphenyl)-1,3-thiazol-4-yl]methanol >95%
500mg
$ 486.00

Matrix Scientific
[2-(4-Methoxyphenyl)-1,3-thiazol-4-yl]methanol >95%
1g
$ 603.00

J&W Pharmlab
[2-(4-Methoxy-phenyl)-thiazol-4-yl]-methanol 96%
5g
$ 698.00

J&W Pharmlab
[2-(4-Methoxy-phenyl)-thiazol-4-yl]-methanol 96%
1g
$ 198.00

J&W Pharmlab
[2-(4-Methoxy-phenyl)-thiazol-4-yl]-methanol 96%
500mg
$ 149.00

J&W Pharmlab
[2-(4-Methoxy-phenyl)-thiazol-4-yl]-methanol 96%
250mg
$ 125.00

J&W Pharmlab
[2-(4-Methoxy-phenyl)-thiazol-4-yl]-methanol 96%
100mg
$ 98.00

Total 14 raw suppliers

Chemical Property of [2-(4-Methoxyphenyl)-1,3-thiazol-4-yl]methanol

Chemical Property:

Melting Point:84-86°C
PSA：70.59000
LogP:2.31100
XLogP3:1.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:221.05104977
Heavy Atom Count:15
Complexity:195

Purity/Quality:

97% ^*data from raw suppliers

[2-(4-methoxyphenyl)-1,3-thiazol-4-yl]methanol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi,Xn
Statements: 22-41
Safety Statements: 26-39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C2=NC(=CS2)CO

Technology Process of [2-(4-Methoxyphenyl)-1,3-thiazol-4-yl]methanol

There total 6 articles about [2-(4-Methoxyphenyl)-1,3-thiazol-4-yl]methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

: 6704-31-0
oxetan-3-one

: 2362-64-3
p-methoxythiobenzamide

: 885279-75-4
2-(4-methoxyphenyl)-4-hydroxymethylthiazole

Guidance literature:: With methanesulfonic acid; carbonic acid dimethyl ester; at 120 ℃; for 2h; Microwave irradiation;
DOI:10.1002/chem.201301011

Reference yield:

: 5720-07-0
4-methoxyphenylboronic acid

: 885279-75-4
2-(4-methoxyphenyl)-4-hydroxymethylthiazole

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / 1,4-dioxane; water / 100 °C / Inert atmosphere

2: sodium tetrahydroborate; methanol / 1 h / 20 °C

With methanol; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium tetrahydroborate; potassium carbonate; In 1,4-dioxane; water;
DOI:10.1021/acs.orglett.9b00563