Dimethyl (4-fluorobenzoyl)phosphonate

Base Information

Chemical Name:Dimethyl (4-fluorobenzoyl)phosphonate
CAS No.:89198-46-9
Molecular Formula:C9H10 F O4 P
Molecular Weight:232.148
Hs Code.:2931900090
DSSTox Substance ID:DTXSID70551019
Nikkaji Number:J2.616.661F
Wikidata:Q82430526
Mol file:89198-46-9.mol

Synonyms:89198-46-9;dimethyl (4-fluorobenzoyl)phosphonate;DIMETHYL(4-FLUOROPHENYLOXOMETHYL)PHOSPHONATE;Phosphonic acid,P-(4-fluorobenzoyl)-, dimethyl ester;dimethoxyphosphoryl-(4-fluorophenyl)methanone;DTXSID70551019;MFCD00800265;AKOS017343619;DIMETHYL 4-FLUOROBENZOYLPHOSPHONATE

Suppliers and Price of Dimethyl (4-fluorobenzoyl)phosphonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
DIMETHYL(4-FLUOROPHENYLOXOMETHYL)PHOSPHONATE 95.00%
5MG
$ 501.97

Total 6 raw suppliers

Chemical Property of Dimethyl (4-fluorobenzoyl)phosphonate

Chemical Property:

PSA：62.41000
LogP:2.45180
XLogP3:1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:232.03007396
Heavy Atom Count:15
Complexity:265

Purity/Quality:

99%+ ^*data from raw suppliers

DIMETHYL(4-FLUOROPHENYLOXOMETHYL)PHOSPHONATE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COP(=O)(C(=O)C1=CC=C(C=C1)F)OC

Technology Process of Dimethyl (4-fluorobenzoyl)phosphonate

There total 1 articles about Dimethyl (4-fluorobenzoyl)phosphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 403-43-0
4-fluorobenzoyl chloride

: 121-45-9
phosphorous acid trimethyl ester

: 89198-46-9
dimethyl 4-fluorobenzoylphosphonate

Guidance literature:: Ambient temperature;
DOI:10.1021/jm00391a027

Reference yield: 88.0%

: 7677-24-9
trimethylsilyl cyanide

: 89198-46-9
dimethyl 4-fluorobenzoylphosphonate

: 1402349-90-9
C₁₃H₁₉FNO₄PSi

Guidance literature:: With 4-nitro-phenol; C₃₅H₄₄N₄O₁₀S; In toluene; at -78 ℃; for 36h; optical yield given as %ee; enantioselective reaction; Inert atmosphere;
DOI:10.1002/anie.201204287

Reference yield: 83.0%

: 75-52-5
nitromethane

: 89198-46-9
dimethyl 4-fluorobenzoylphosphonate

: [1-(4-fluoro-phenyl)-1-hydroxy-2-nitro-ethyl]-phosphonic acid dimethyl ester

Guidance literature:: 4-[(R)-((2S,4S,5R)-5-ethenyl-1-azabicyclo-[2.2.2]octan-2-yl)(hydroxy)methyl]quinolin-6-ol; In tetrahydrofuran; at 0 ℃; for 16h;
DOI:10.1021/ol070209i