6-(5-chloro-2-hydroxy-3-iodophenyl)-4-(2-chloro-5-(trifluoromethyl)phenyl)-2-oxo-1,2-dihydro-3-pyridinecarbonitrile

Base Information

Chemical Name:6-(5-chloro-2-hydroxy-3-iodophenyl)-4-(2-chloro-5-(trifluoromethyl)phenyl)-2-oxo-1,2-dihydro-3-pyridinecarbonitrile
CAS No.:931112-51-5
Molecular Formula:C₁₉H₈Cl₂F₃IN₂O₂
Molecular Weight:551.09
Hs Code.:

Synonyms:6-(5-chloro-2-hydroxy-3-iodophenyl)-4-(2-chloro-5-(trifluoromethyl)phenyl)-2-oxo-1,2-dihydro-3-pyridinecarbonitrile

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Chemical Property of 6-(5-chloro-2-hydroxy-3-iodophenyl)-4-(2-chloro-5-(trifluoromethyl)phenyl)-2-oxo-1,2-dihydro-3-pyridinecarbonitrile

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Technology Process of 6-(5-chloro-2-hydroxy-3-iodophenyl)-4-(2-chloro-5-(trifluoromethyl)phenyl)-2-oxo-1,2-dihydro-3-pyridinecarbonitrile

There total 1 articles about 6-(5-chloro-2-hydroxy-3-iodophenyl)-4-(2-chloro-5-(trifluoromethyl)phenyl)-2-oxo-1,2-dihydro-3-pyridinecarbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 931112-50-4
6-(5-chloro-2-hydroxyphenyl)-4-(2-chloro-5-(trifluoromethyl)phenyl)-2-oxo-1,2-dihydro-3-pyridinecarbonitrile

: 931112-51-5
6-(5-chloro-2-hydroxy-3-iodophenyl)-4-(2-chloro-5-(trifluoromethyl)phenyl)-2-oxo-1,2-dihydro-3-pyridinecarbonitrile

Guidance literature:: With N-iodo-succinimide; In acetonitrile; Heating;
DOI:10.1016/j.bmcl.2007.03.042

Reference yield:

: 931112-51-5
6-(5-chloro-2-hydroxy-3-iodophenyl)-4-(2-chloro-5-(trifluoromethyl)phenyl)-2-oxo-1,2-dihydro-3-pyridinecarbonitrile

: 201230-82-2
carbon monoxide

: 931112-56-0
6-(5-chloro-3-formyl-2-hydroxyphenyl)-4-(2-chloro-5-(trifluoromethyl)phenyl)-2-oxo-1,2-dihydro-3-pyridinecarbonitrile

Guidance literature:: With triethylsilane; 1,1'-bis-(diphenylphosphino)ferrocene; triethylamine; palladium diacetate; In N,N-dimethyl-formamide; at 80 ℃;
DOI:10.1016/j.bmcl.2007.03.042

Reference yield:

: 931112-51-5
6-(5-chloro-2-hydroxy-3-iodophenyl)-4-(2-chloro-5-(trifluoromethyl)phenyl)-2-oxo-1,2-dihydro-3-pyridinecarbonitrile

: 79-10-7
acrylic acid

: 3-(5-chloro-3-(4-(2-chloro-5-(trifluoromethyl)phenyl)-5-cyano-6-oxo-1,6-dihydropyridin-2-yl)-2-hydroxyphenyl)-2-propenoic acid

Guidance literature:: With triethylamine; palladium dichloride; tri tert-butylphosphoniumtetrafluoroborate; In N,N-dimethyl-formamide; at 55 ℃; for 24h;