dimethyl (2E,2'E)-3,3'-[4-(4-chlorophenyl)pyridine-2,6-diyl]bisprop-2-enoate

Base Information

Chemical Name:dimethyl (2E,2'E)-3,3'-[4-(4-chlorophenyl)pyridine-2,6-diyl]bisprop-2-enoate
CAS No.:1364054-33-0
Molecular Formula:C₁₉H₁₆ClNO₄
Molecular Weight:357.793
Hs Code.:

Synonyms:dimethyl (2E,2'E)-3,3'-[4-(4-chlorophenyl)pyridine-2,6-diyl]bisprop-2-enoate

Suppliers and Price of dimethyl (2E,2'E)-3,3'-[4-(4-chlorophenyl)pyridine-2,6-diyl]bisprop-2-enoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of dimethyl (2E,2'E)-3,3'-[4-(4-chlorophenyl)pyridine-2,6-diyl]bisprop-2-enoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of dimethyl (2E,2'E)-3,3'-[4-(4-chlorophenyl)pyridine-2,6-diyl]bisprop-2-enoate

There total 2 articles about dimethyl (2E,2'E)-3,3'-[4-(4-chlorophenyl)pyridine-2,6-diyl]bisprop-2-enoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 1364054-24-9
dimethyl (2E,2'E)-3,3'-(4-bromopyridine-2,6-diyl)bisprop-2-enoate

: 1679-18-1
4-Chlorophenylboronic acid

: 1364054-33-0
dimethyl (2E,2'E)-3,3'-[4-(4-chlorophenyl)pyridine-2,6-diyl]bisprop-2-enoate

Guidance literature:: With potassium fluoride; potassium carbonate; triphenylphosphine; In 1,2-dimethoxyethane; water; at 95 ℃; for 48h;
DOI:10.1002/hlca.201100195

Reference yield:

: 128184-01-0
4-bromo pyridine-2,6-dicarbaldehyde

: 1364054-33-0
dimethyl (2E,2'E)-3,3'-[4-(4-chlorophenyl)pyridine-2,6-diyl]bisprop-2-enoate

Guidance literature:: Multi-step reaction with 2 steps

1.1: 1,8-diazabicyclo[5.4.0]undec-7-ene; lithium chloride / acetonitrile / 0.33 h / 0 °C

1.2: 19.5 h / 0 - 20 °C

2.1: potassium fluoride; potassium carbonate; triphenylphosphine / 1,2-dimethoxyethane; water / 48 h / 95 °C

With potassium fluoride; potassium carbonate; 1,8-diazabicyclo[5.4.0]undec-7-ene; triphenylphosphine; lithium chloride; In 1,2-dimethoxyethane; water; acetonitrile; 1.1: Horner-Wadsworth-Emmons olefination / 1.2: Horner-Wadsworth-Emmons olefination / 2.1: Suzuki coupling;
DOI:10.1002/hlca.201100195

Reference yield: 89.0%

: 1364054-33-0
dimethyl (2E,2'E)-3,3'-[4-(4-chlorophenyl)pyridine-2,6-diyl]bisprop-2-enoate

: 1364054-49-8
dimethyl 3,3'-[4-(4-chlorophenyl)pyridine-2,6-diyl]dipropanoate

Guidance literature:: With palladium on activated charcoal; hydrogen; In methanol; at 60 ℃; for 15h; under 760.051 Torr;
DOI:10.1002/hlca.201100195