Lithium; (Z)-1-(phenyl-trimethylsilanyl-amino)-propene-1-thiolate

Base Information

• Chemical Name: Lithium; (Z)-1-(phenyl-trimethylsilanyl-amino)-propene-1-thiolate
• CAS No.: 82080-81-7
• Molecular Formula: C₁₂H₁₈NSSi*Li
• Molecular Weight: 243.374
• Mol file: 82080-81-7.mol

Synonyms:Lithium; (Z)-1-(phenyl-trimethylsilanyl-amino)-propene-1-thiolate

Chemical Property of Lithium; (Z)-1-(phenyl-trimethylsilanyl-amino)-propene-1-thiolate

Chemical Property:

Purity/Quality:

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Technology Process of Lithium; (Z)-1-(phenyl-trimethylsilanyl-amino)-propene-1-thiolate

There total 1 articles about Lithium; (Z)-1-(phenyl-trimethylsilanyl-amino)-propene-1-thiolate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

chloro-trimethyl-silane (75-77-4) + N-phenylpropanethioamide (2955-69-3) → Lithium; (Z)-1-(phenyl-trimethylsilanyl-amino)-propene-1-thiolate (82080-81-7)

Guidance literature:

With n-butyllithium; In tetrahydrofuran; at 0 ℃; 1.) 1 h, 2.) 1 h;

DOI:10.1021/ja00378a046

Reference yield: 51.0%

(E)-2-butenyl 4-methylbenzenesulfonate (76454-93-8) + Lithium; (Z)-1-(phenyl-trimethylsilanyl-amino)-propene-1-thiolate (82080-81-7) → erythro-N-phenyl-2,3-dimethylthio-4-pentenoylamide (82080-82-8)

Guidance literature:

1.) -78 deg C, 2.) room temperature, 2 days;

DOI:10.1021/ja00378a046

Reference yield: 50.0%

(Z)-2-butenyl 4-methylbenzenesulfonate (76454-94-9) + Lithium; (Z)-1-(phenyl-trimethylsilanyl-amino)-propene-1-thiolate (82080-81-7) → threo-N-phenyl-2,3-dimethylthio-4-pentenoylamide (82080-83-9)

Guidance literature:

1.) -78 deg C, 2.) 65 deg C, 32 h;

DOI:10.1021/ja00378a046

upstream raw materials:

chloro-trimethyl-silane

N-phenylpropanethioamide

Downstream raw materials:

threo-N-phenyl-2,3-dimethylthio-4-pentenoylamide

erythro-N-phenyl-2,3-dimethylthio-4-pentenoylamide