H-TYR-GLY-GLY-PHE-LEU-LYS-OH ACETATE SALT

Base Information

Chemical Name:H-TYR-GLY-GLY-PHE-LEU-LYS-OH ACETATE SALT
CAS No.:83404-43-7
Molecular Formula:C34H49 N7 O8
Molecular Weight:683.805
Hs Code.:
Mol file:83404-43-7.mol

Synonyms:1-7-a-Neoendorphin (swine),6-de-L-arginine- (9CI); a-Neoendorphin (pig), 6-de-L-arginine-8-de-L-tyrosine-9-de-L-proline-10-de-L-lysine-;204: PN: WO0069900 SEQID: 876 unclaimed sequence; 45: PN: WO0222860 SEQID: 42unclaimed sequence; 701: PN: US20090175821 SEQID: 876 claimed protein;[Leu5-Lys6]enkephalin

Suppliers and Price of H-TYR-GLY-GLY-PHE-LEU-LYS-OH ACETATE SALT

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 10 raw suppliers

Chemical Property of H-TYR-GLY-GLY-PHE-LEU-LYS-OH ACETATE SALT

Chemical Property:

PSA：292.37000
LogP:2.89720
Storage Temp.:-15°C

Purity/Quality:: 99%, ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of H-TYR-GLY-GLY-PHE-LEU-LYS-OH ACETATE SALT

There total 8 articles about H-TYR-GLY-GLY-PHE-LEU-LYS-OH ACETATE SALT which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 24458-14-8
Lys(Z)-OBzl

: 83404-43-7
Tyrosyl-glycyl-glycyl-phenylalanyl-leucyl-lysine

Guidance literature:: Multi-step reaction with 3 steps

1: 57 percent / 1-hydroxybenzotriazol, dicyclohexylcarbodiimide / dimethylformamide / 1 h / -20 - 0 °C / O deg C, overnight

2: ammonium formate / 10percent palladium on carbon / methanol / 3 h / Ambient temperature

3: anisol, trifluoroacetic acid / 1 h / Ambient temperature

With ammonium formate; benzotriazol-1-ol; methoxybenzene; dicyclohexyl-carbodiimide; trifluoroacetic acid; palladium on activated charcoal; In methanol; N,N-dimethyl-formamide;
DOI:10.1135/cccc19851329

Reference yield:

: 3978-80-1
Boc-Tyr-OH

: 83404-43-7
Tyrosyl-glycyl-glycyl-phenylalanyl-leucyl-lysine

Guidance literature:: Multi-step reaction with 7 steps

1: 72 percent / 1-hydroxybenzotriazol, dicyclohexylcarbodiimide / dimethylformamide / 1 h / 0 °C

2: hydrogen / palladium black / 2-methyl-propan-2-ol / 8 h

3: dicyclohexylcarbodiimide / CHCl₃ / 3 h / -20 - 0 °C / r.t., overnight

4: 86 percent / hydrogen / palladium black / 2-methyl-propan-2-ol / 16 h

5: 57 percent / 1-hydroxybenzotriazol, dicyclohexylcarbodiimide / dimethylformamide / 1 h / -20 - 0 °C / O deg C, overnight

6: ammonium formate / 10percent palladium on carbon / methanol / 3 h / Ambient temperature

7: anisol, trifluoroacetic acid / 1 h / Ambient temperature

With hydrogen; ammonium formate; benzotriazol-1-ol; methoxybenzene; dicyclohexyl-carbodiimide; trifluoroacetic acid; palladium on activated charcoal; palladium; In methanol; chloroform; N,N-dimethyl-formamide; tert-butyl alcohol;
DOI:10.1135/cccc19851329

Reference yield:

: 64963-27-5
N-tert-butyloxycarbonyl-L-tyrosyl-glycyl-glycyl-L-phenylalanyl-L-leucine

: 83404-43-7
Tyrosyl-glycyl-glycyl-phenylalanyl-leucyl-lysine

Guidance literature:: Multi-step reaction with 3 steps

1: 57 percent / 1-hydroxybenzotriazol, dicyclohexylcarbodiimide / dimethylformamide / 1 h / -20 - 0 °C / O deg C, overnight

2: ammonium formate / 10percent palladium on carbon / methanol / 3 h / Ambient temperature

3: anisol, trifluoroacetic acid / 1 h / Ambient temperature

With ammonium formate; benzotriazol-1-ol; methoxybenzene; dicyclohexyl-carbodiimide; trifluoroacetic acid; palladium on activated charcoal; In methanol; N,N-dimethyl-formamide;
DOI:10.1135/cccc19851329