dimethyl 2-[2-(4-fluorophenyl)-2-oxoethyl]-2-[2-[4-(methylsulfonyl)phenyl]-2-oxoethyl]propanedioate

Base Information

Chemical Name:dimethyl 2-[2-(4-fluorophenyl)-2-oxoethyl]-2-[2-[4-(methylsulfonyl)phenyl]-2-oxoethyl]propanedioate
CAS No.:159429-82-0
Molecular Formula:C₂₂H₂₁FO₈S
Molecular Weight:464.468
Hs Code.:

Synonyms:dimethyl 2-[2-(4-fluorophenyl)-2-oxoethyl]-2-[2-[4-(methylsulfonyl)phenyl]-2-oxoethyl]propanedioate

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Chemical Property of dimethyl 2-[2-(4-fluorophenyl)-2-oxoethyl]-2-[2-[4-(methylsulfonyl)phenyl]-2-oxoethyl]propanedioate

Chemical Property:

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Technology Process of dimethyl 2-[2-(4-fluorophenyl)-2-oxoethyl]-2-[2-[4-(methylsulfonyl)phenyl]-2-oxoethyl]propanedioate

There total 5 articles about dimethyl 2-[2-(4-fluorophenyl)-2-oxoethyl]-2-[2-[4-(methylsulfonyl)phenyl]-2-oxoethyl]propanedioate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 403-29-2
2-bromo-4'-fluoroacetophenone

: 108-59-8
malonic acid dimethyl ester

: 50413-24-6
2-bromo-1-(4-methanesulfonylphenyl)ethanone

: 159429-83-1
1-<2-(4-fluorophenyl)-4,4-dicarbomethoxycyclopenten-1-yl>-4-(methylsulfonyl)benzene

: 159429-82-0
dimethyl 2-[2-(4-fluorophenyl)-2-oxoethyl]-2-[2-[4-(methylsulfonyl)phenyl]-2-oxoethyl]propanedioate

Guidance literature:: In N,N-dimethyl-formamide;

Reference yield:

: 1026591-03-6
dimethyl 2-(2-(4-fluorophenyl)-2-oxoethyl)malonate

: 50413-24-6
2-bromo-1-(4-methanesulfonylphenyl)ethanone

: 159429-82-0
dimethyl 2-[2-(4-fluorophenyl)-2-oxoethyl]-2-[2-[4-(methylsulfonyl)phenyl]-2-oxoethyl]propanedioate

Guidance literature:: With sodium hydride; In N,N-dimethyl-formamide; at -20 ℃;
DOI:10.1021/jm00049a005

Reference yield:

: 403-29-2
2-bromo-4'-fluoroacetophenone

: 159429-82-0
dimethyl 2-[2-(4-fluorophenyl)-2-oxoethyl]-2-[2-[4-(methylsulfonyl)phenyl]-2-oxoethyl]propanedioate

Guidance literature:: Multi-step reaction with 2 steps

1: NaH / dimethylformamide / -20 °C

2: NaH / dimethylformamide / -20 °C

With sodium hydride; In N,N-dimethyl-formamide;
DOI:10.1021/jm00049a005