7-(benzyloxy)-2-(3',4'-bis(benzyloxy)phenyl)-5-hydroxy-4H-chromen-4-one

Base Information

• Chemical Name: 7-(benzyloxy)-2-(3',4'-bis(benzyloxy)phenyl)-5-hydroxy-4H-chromen-4-one
• CAS No.: 1201807-92-2
• Molecular Formula: C₃₆H₂₈O₆
• Molecular Weight: 556.615
• Mol file: 1201807-92-2.mol

Synonyms:7-(benzyloxy)-2-(3',4'-bis(benzyloxy)phenyl)-5-hydroxy-4H-chromen-4-one

Chemical Property of 7-(benzyloxy)-2-(3',4'-bis(benzyloxy)phenyl)-5-hydroxy-4H-chromen-4-one

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 7-(benzyloxy)-2-(3',4'-bis(benzyloxy)phenyl)-5-hydroxy-4H-chromen-4-one

There total 1 articles about 7-(benzyloxy)-2-(3',4'-bis(benzyloxy)phenyl)-5-hydroxy-4H-chromen-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-chromen-4-on (491-70-3) + benzyl bromide (100-39-0) → 7-(benzyloxy)-2-(3',4'-bis(benzyloxy)phenyl)-5-hydroxy-4H-chromen-4-one (1201807-92-2)

Guidance literature:

2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-chromen-4-on; With potassium carbonate; potassium iodide; In N,N-dimethyl-formamide; at 20 ℃; for 1h; Inert atmosphere;

benzyl bromide; In N,N-dimethyl-formamide; at 80 ℃; for 10h; Inert atmosphere;

DOI:10.1039/c6ra20851g

Reference yield: 99.0%

7-(benzyloxy)-2-(3',4'-bis(benzyloxy)phenyl)-5-hydroxy-4H-chromen-4-one (1201807-92-2) + acetyl chloride (75-36-5) → 7-(benzyloxy)-2-(3,4-bis(benzyloxy)phenyl)-4-oxo-4H-chromen-5-yl acetate (1201807-93-3)

Guidance literature:

7-(benzyloxy)-2-(3',4'-bis(benzyloxy)phenyl)-5-hydroxy-4H-chromen-4-one; With sodium hydride; In N,N-dimethyl-formamide; for 0.5h; Inert atmosphere;

acetyl chloride; In N,N-dimethyl-formamide; at 20 ℃; for 2h; Inert atmosphere;

DOI:10.1016/j.bmc.2010.09.049

Reference yield: 98.7%

7-(benzyloxy)-2-(3',4'-bis(benzyloxy)phenyl)-5-hydroxy-4H-chromen-4-one (1201807-92-2) + ethyl iodide (75-03-6) → 7-(benzyloxy)-2-(3,4-bis(benzyloxy)phenyl)-5-ethoxy-4H-chromen-4-one (1201808-02-7)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 75 ℃; for 12h; Inert atmosphere;

DOI:10.1016/j.bmc.2010.09.049

upstream raw materials:

2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-chromen-4-on

benzyl bromide

Downstream raw materials:

7-(benzyloxy)-2-(3,4-bis(benzyloxy)phenyl)-4-oxo-4H-chromen-5-yl 4-methylpentanoate

7-(benzyloxy)-2-(3,4-bis(benzyloxy)phenyl)-4-oxo-4H-chromen-5-yl propionate

7-(benzyloxy)-2-(3,4-bis(benzyloxy)phenyl)-4-oxo-4H-chromen-5-yl benzoate

7-(benzyloxy)-2-(3,4-bis(benzyloxy)phenyl)-4-oxo-4H-chromen-5-yl 4-methylbenzoate