4-BROMOFURAN-2-CARBOXALDEHYDE ETHYLENE GLYCOL ACETAL

Base Information

• Chemical Name: 4-BROMOFURAN-2-CARBOXALDEHYDE ETHYLENE GLYCOL ACETAL
• CAS No.: 83953-42-8
• Molecular Formula: C7H7 Br O3
• Molecular Weight: 219.03
• Hs Code.: 2932999099
• Mol file: 83953-42-8.mol

Synonyms:2-(4-Bromo-2-furyl)-1,3-dioxolane

Chemical Property of 4-BROMOFURAN-2-CARBOXALDEHYDE ETHYLENE GLYCOL ACETAL

Chemical Property:

• PSA: 31.60000
• LogP: 2.08750

Purity/Quality:

98%min ^*data from raw suppliers

4-BROMOFURAN-2-CARBOXALDEHYDE ETHYLENE GLYCOL ACETAL 97.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-BROMOFURAN-2-CARBOXALDEHYDE ETHYLENE GLYCOL ACETAL

There total 2 articles about 4-BROMOFURAN-2-CARBOXALDEHYDE ETHYLENE GLYCOL ACETAL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

4-bromo-2-furancarbaldehyde (21921-76-6) + ethylene glycol (107-21-1) → 4-bromo-2-furancarboxyaldehyde ethylene acetal (83953-42-8)

Guidance literature:

With toluene-4-sulfonic acid; In benzene; for 6h; Heating / reflux;

Reference yield:

2-(4,5-dibromo-2-furanyl)-1,3-dioxolane (873583-41-6) → 2-(4-bromo-2-furanyl)-1,3-dioxolane (32529-50-3) + 4-bromo-2-furancarboxyaldehyde ethylene acetal (83953-42-8)

Guidance literature:

With n-butyllithium; In tetrahydrofuran; hexane; at -70 - -60 ℃; Further Variations:; Temperatures; Product distribution;

DOI:10.1002/jhet.5570420723

Reference yield: 95.0%

3β-benzyloxy-5β-androst-15-en-17-one (73336-58-0) + 4-bromo-2-furancarboxyaldehyde ethylene acetal (83953-42-8) → 4-(3'β-benzyloxy-17'β-hydroxy-5'β-androst-15'-en-17'α-yl)furan-2-carbaldehyde ethylene acetal (85393-98-2)

Guidance literature:

With n-butyllithium; In diethyl ether; at -70 ℃;

DOI:10.1039/c39820001213

upstream raw materials:

2-(4,5-dibromo-2-furanyl)-1,3-dioxolane

4-bromo-2-furancarbaldehyde

ethylene glycol

Downstream raw materials:

4-(3'β-benzyloxy-17'β-hydroxy-5'β-androst-15'-en-17'α-yl)furan-2-carbaldehyde ethylene acetal

4-(3'α-benzyloxy-17'-hydroxy-5'β-estr-15'-en-17'-yl)furan-2-carboxyaldehyde ethylene acetal

(5-formylfuran-3-yl)boronic acid

5-formyl-furan-3-carboxylic acid