dimethyl [3-chloro-5-(trifluoromethyl)pyridin-2-yl]({[2-(trifluoromethyl)benzoyl]amino}methyl)malonate

Base Information

Chemical Name:dimethyl [3-chloro-5-(trifluoromethyl)pyridin-2-yl]({[2-(trifluoromethyl)benzoyl]amino}methyl)malonate
CAS No.:895525-76-5
Molecular Formula:C₂₀H₁₅ClF₆N₂O₅
Molecular Weight:512.793
Hs Code.:

Synonyms:dimethyl [3-chloro-5-(trifluoromethyl)pyridin-2-yl]({[2-(trifluoromethyl)benzoyl]amino}methyl)malonate

Suppliers and Price of dimethyl [3-chloro-5-(trifluoromethyl)pyridin-2-yl]({[2-(trifluoromethyl)benzoyl]amino}methyl)malonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 13 raw suppliers

Chemical Property of dimethyl [3-chloro-5-(trifluoromethyl)pyridin-2-yl]({[2-(trifluoromethyl)benzoyl]amino}methyl)malonate

Chemical Property:

Density:1.53 at 20℃

Purity/Quality:: 99.9% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

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Technology Process of dimethyl [3-chloro-5-(trifluoromethyl)pyridin-2-yl]({[2-(trifluoromethyl)benzoyl]amino}methyl)malonate

There total 8 articles about dimethyl [3-chloro-5-(trifluoromethyl)pyridin-2-yl]({[2-(trifluoromethyl)benzoyl]amino}methyl)malonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 895525-72-1
{[2-(trifluoromethyl)benzoyl]amino}methyl acetate

: 477859-76-0
1,3-dimethyl 2-(3-chloro-5-trifluoromethylpyridine)malonate

: 895525-76-5
dimethyl [3-chloro-5-(trifluoromethyl)pyridin-2-yl]({[2-(trifluoromethyl)benzoyl]amino}methyl)malonate

Guidance literature:: With sodium acetate; at 62.5 ℃; for 6h; Temperature;

Reference yield:

: 895525-72-1
{[2-(trifluoromethyl)benzoyl]amino}methyl acetate

: C₁₁H₈ClF₃NO₄^(1-)*K⁽¹⁺⁾

: 895525-76-5
dimethyl [3-chloro-5-(trifluoromethyl)pyridin-2-yl]({[2-(trifluoromethyl)benzoyl]amino}methyl)malonate

Guidance literature:: With acetic acid; at 60 - 80 ℃;

Reference yield:

: 108-59-8
malonic acid dimethyl ester

: 895525-76-5
dimethyl [3-chloro-5-(trifluoromethyl)pyridin-2-yl]({[2-(trifluoromethyl)benzoyl]amino}methyl)malonate

Guidance literature:: Multi-step reaction with 2 steps

1: potassium hydroxide / N,N-dimethyl acetamide / 62 °C

2: acetic acid / 60 - 80 °C

With acetic acid; potassium hydroxide; In N,N-dimethyl acetamide;