5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine

Base Information

Chemical Name:5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine
CAS No.:76512-82-8
Molecular Formula:C30H31 N3 O6
Molecular Weight:529.593
Hs Code.:
DSSTox Substance ID:DTXSID80473339
Nikkaji Number:J845.152D
Wikidata:Q82302675
Mol file:76512-82-8.mol

Synonyms:76512-82-8;5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine;4-amino-1-[(2R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxyoxolan-2-yl]pyrimidin-2-one;4-Amino-1-((2R,4S,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxytetrahydrofuran-2-yl)pyrimidin-2(1H)-one;DMT-dC;SCHEMBL6885492;DTXSID80473339;MFCD06796700;AKOS027439697;EN300-7400791;5'-o-(4,4'-Dimethoxytrityl)-2'-deoxycytidine min. 99,5%;4-amino-1-[(2R,4S,5R)-5-{[bis(4-methoxyphenyl)(phenyl)methoxy]methyl}-4-hydroxyoxolan-2-yl]-1,2-dihydropyrimidin-2-one

Suppliers and Price of 5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
4-Amino-1-((2R,4S,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxytetrahydrofuran-2-yl)pyrimidin-2(1H)-one 97%
5g
$ 508.00

Biosynth Carbosynth
2'-Deoxy-5'-O-DMT-cytidine
10 g
$ 480.00

Biosynth Carbosynth
2'-Deoxy-5'-O-DMT-cytidine
5 g
$ 325.00

Biosynth Carbosynth
2'-Deoxy-5'-O-DMT-cytidine
1 g
$ 95.00

Biosynth Carbosynth
2'-Deoxy-5'-O-DMT-cytidine
500 mg
$ 70.00

Biosynth Carbosynth
2'-Deoxy-5'-O-DMT-cytidine
250 mg
$ 50.00

AK Scientific
5'-o-(4,4'-dimethoxytrityl)-2'-deoxycytidine
10g
$ 698.00

Total 9 raw suppliers

Chemical Property of 5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine

Chemical Property:

PSA：118.06000
LogP:4.08100
Storage Temp.:Store dry at 2-8°C
XLogP3:2.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:9
Exact Mass:529.22128572
Heavy Atom Count:39
Complexity:850

Purity/Quality:

99.3% ^*data from raw suppliers

4-Amino-1-((2R,4S,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxytetrahydrofuran-2-yl)pyrimidin-2(1H)-one 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)OCC4C(CC(O4)N5C=CC(=NC5=O)N)O
Isomeric SMILES:COC1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)OC[C@@H]4[C@H](C[C@@H](O4)N5C=CC(=NC5=O)N)O

Technology Process of 5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine

There total 25 articles about 5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 329781-63-7
2-Azidomethyl-N-(1-{(2R,4S,5R)-5-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-hydroxy-tetrahydro-furan-2-yl}-2-oxo-1,2-dihydro-pyrimidin-4-yl)-benzamide

: 76512-82-8
5'-O-(4,4'-dimethoxytrityl)deoxycytidine

Guidance literature:: With diphenyl(methyl)phosphine; In 1,4-dioxane; water; at 20 ℃; for 0.333333h;
DOI:10.1016/S0040-4039(00)02183-3

Reference yield: 85.0%

: 117032-49-2
4-(1,2,4-triazol-1-yl)-5'-O-(4,4'-dimethoxytriphenylmethyl)-3'-O-trimethylsilyl thymidine

: 76512-82-8
5'-O-(4,4'-dimethoxytrityl)deoxycytidine

Guidance literature:: With ammonium hydroxide; In 1,4-dioxane;

Reference yield: 85.0%

: 40615-36-9
4,4'-dimethoxytrityl chloride

: 951-77-9
2'-Deoxycytidine

: 76512-82-8
5'-O-(4,4'-dimethoxytrityl)deoxycytidine

Guidance literature:: With 1H-imidazole; methanesulfonic acid; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20 ℃; for 2h;
DOI:10.1021/jo990051i