1-{[bis(4-methoxyphenyl)(phenyl)methyl]sulfanyl}ethan-1-one

Base Information

• Chemical Name: 1-{[bis(4-methoxyphenyl)(phenyl)methyl]sulfanyl}ethan-1-one
• CAS No.: 177738-45-3
• Molecular Formula: C₂₃H₂₂O₃S
• Molecular Weight: 378.492
• Mol file: 177738-45-3.mol

Synonyms:1-{[bis(4-methoxyphenyl)(phenyl)methyl]sulfanyl}ethan-1-one

Chemical Property of 1-{[bis(4-methoxyphenyl)(phenyl)methyl]sulfanyl}ethan-1-one

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 1-{[bis(4-methoxyphenyl)(phenyl)methyl]sulfanyl}ethan-1-one

There total 2 articles about 1-{[bis(4-methoxyphenyl)(phenyl)methyl]sulfanyl}ethan-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

4,4'-dimethoxytrityl chloride (40615-36-9) + potassium thioacetate (10387-40-3) → 1-{[bis(4-methoxyphenyl)(phenyl)methyl]sulfanyl}ethan-1-one (177738-45-3)

Guidance literature:

In acetonitrile; at 25 ℃; for 18h;

DOI:10.1021/acs.orglett.8b00996

Reference yield:

4,4'-dimethoxytrityl chloride (40615-36-9) + sodium hydrogencarbonate (144-55-8) + tiolacetic acid (507-09-5) → 1-{[bis(4-methoxyphenyl)(phenyl)methyl]sulfanyl}ethan-1-one (177738-45-3)

Guidance literature:

With triethylamine; In dichloromethane; water;

Reference yield: 92.0%

1-{[bis(4-methoxyphenyl)(phenyl)methyl]sulfanyl}ethan-1-one (177738-45-3) → 4,4'-dimethoxytriphenylmethanethiol (263746-51-6)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether; at 0 - 25 ℃; for 5.25h; Inert atmosphere;

DOI:10.1021/acs.orglett.8b00996

upstream raw materials:

4,4'-dimethoxytrityl chloride

sodium hydrogencarbonate

tiolacetic acid

potassium thioacetate

Downstream raw materials:

4,4'-dimethoxytriphenylmethanethiol