17-(1,5-dimethyl-hexyl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1Hcyclopenta[a]phenanthren-3-yl diphenyl phosphate

Base Information

• Chemical Name: 17-(1,5-dimethyl-hexyl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1Hcyclopenta[a]phenanthren-3-yl diphenyl phosphate
• CAS No.: 24352-63-4
• Molecular Formula: C₃₉H₅₅O₄P
• Molecular Weight: 618.837
• Mol file: 24352-63-4.mol

Synonyms:17-(1,5-dimethyl-hexyl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1Hcyclopenta[a]phenanthren-3-yl diphenyl phosphate

Chemical Property of 17-(1,5-dimethyl-hexyl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1Hcyclopenta[a]phenanthren-3-yl diphenyl phosphate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 17-(1,5-dimethyl-hexyl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1Hcyclopenta[a]phenanthren-3-yl diphenyl phosphate

There total 2 articles about 17-(1,5-dimethyl-hexyl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1Hcyclopenta[a]phenanthren-3-yl diphenyl phosphate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

cholesterol (57-88-5) + chlorophosphoric acid diphenyl ester (2524-64-3) → 17-(1,5-dimethyl-hexyl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1Hcyclopenta[a]phenanthren-3-yl diphenyl phosphate (24352-63-4)

Guidance literature:

With tris(pentafluorophenyl)borate; triethylamine; In dichloromethane; at 20 ℃; for 0.5h;

DOI:10.1002/cjoc.201200264

Reference yield:

cholesterol (57-88-5) + chlorophosphoric acid diphenyl ester (2524-64-3) → 17-(1,5-dimethyl-hexyl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1Hcyclopenta[a]phenanthren-3-yl diphenyl phosphate (24352-63-4)

Guidance literature:

With pyridine;

DOI:10.1039/jr9540002301

Reference yield: 67.0%

methanol (67-56-1) + 17-(1,5-dimethyl-hexyl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1Hcyclopenta[a]phenanthren-3-yl diphenyl phosphate (24352-63-4) → cholesteryl methyl ether (1174-92-1)

Guidance literature:

at 25 ℃; for 1h; Molecular sieve; Electrochemical reaction; Inert atmosphere;

DOI:10.1016/j.steroids.2016.05.011

upstream raw materials:

cholesterol

chlorophosphoric acid diphenyl ester

cholesterol

Downstream raw materials:

phosphoric acid cholesteryl ester-phenyl ester

3β-O-(1’,2’:3’,4’-di-O-isopropylidene-α-D-galactopyranos-6’-yl)cholest-5-ene

cholesterol

cholesteryl methyl ether