C₁₂H₁₀BrF₄NO₃

Base Information

Chemical Name:C₁₂H₁₀BrF₄NO₃
CAS No.:1443035-37-7
Molecular Formula:C₁₂H₁₀BrF₄NO₃
Molecular Weight:372.114
Hs Code.:

C<sub>12</sub>H<sub>10</sub>BrF<sub>4</sub>NO<sub>3</sub>

Synonyms:C₁₂H₁₀BrF₄NO₃

Suppliers and Price of C₁₂H₁₀BrF₄NO₃

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of C₁₂H₁₀BrF₄NO₃

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of C₁₂H₁₀BrF₄NO₃

There total 7 articles about C₁₂H₁₀BrF₄NO₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 1443035-35-5
(3R)-3-(5-bromo-2-fluorophenyl)-3-methylmorpholine-2,5-dione

: 81290-20-2
(trifluoromethyl)trimethylsilane

: 1443035-37-7
C₁₂H₁₀BrF₄NO₃

Guidance literature:: With tetrabutylammonium triphenyldifluorosilicate; In tetrahydrofuran; at 20 ℃; for 0.333333h;

Reference yield:

: 1266784-23-9
(RS)-2-amino-2-(5-bromo-2-fluoro-phenyl)-propionic acid

: 1443035-37-7
C₁₂H₁₀BrF₄NO₃

Guidance literature:: Multi-step reaction with 5 steps

1: sulfuric acid / 48 h / Reflux

2: sodium hydroxide / water; tetrahydrofuran / 4 h / 20 °C

3: sodium hydroxide / water; 1,4-dioxane / pH 10 - 11 / Cooling

4: sodium hydrogencarbonate / N,N-dimethyl-formamide / 3 h / 80 °C

5: tetrabutylammonium triphenyldifluorosilicate / tetrahydrofuran / 0.33 h / 20 °C

With sulfuric acid; sodium hydrogencarbonate; tetrabutylammonium triphenyldifluorosilicate; sodium hydroxide; In tetrahydrofuran; 1,4-dioxane; water; N,N-dimethyl-formamide;

Reference yield:

: 1350523-51-1
rac-2-amino-2-(5-bromo-2-fluoro-phenyl)-propionitrile

: 1443035-37-7
C₁₂H₁₀BrF₄NO₃

Guidance literature:: Multi-step reaction with 6 steps

1: hydrogenchloride; acetic acid / water / 16 h / Reflux

2: sulfuric acid / 48 h / Reflux

3: sodium hydroxide / water; tetrahydrofuran / 4 h / 20 °C

4: sodium hydroxide / water; 1,4-dioxane / pH 10 - 11 / Cooling

5: sodium hydrogencarbonate / N,N-dimethyl-formamide / 3 h / 80 °C

6: tetrabutylammonium triphenyldifluorosilicate / tetrahydrofuran / 0.33 h / 20 °C

With hydrogenchloride; sulfuric acid; sodium hydrogencarbonate; acetic acid; tetrabutylammonium triphenyldifluorosilicate; sodium hydroxide; In tetrahydrofuran; 1,4-dioxane; water; N,N-dimethyl-formamide;